kaempferitrin   Click here for help

GtoPdb Ligand ID: 13277

Synonyms: kaempferol 3,7-dirhamnoside | lespedin | lespenefril
Compound class: Natural product or derivative
Comment: Kaempferitrin is a plant-derived flavonoid. In vivo anti-depressant effects have been demonstrated, with 5-HT1A receptor as the suspected primary molecular target [1].
2D Structure
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2D Structure

An image of the ligand's 2D structure. For small molecules with SMILES these are drawn using the NCI/CADD Chemical Identifier Resolver. Click on the image to access the chemical structure search tool with the ligand pre-loaded in the structure editor. For other types of ligands, e.g. longer nucleotides and peptides, a manually drawn representation of the molecule may be provided.

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Physico-chemical Properties
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Physico-chemical Properties

Calculated molecular properties are available for small molecules and natural products (not peptides). Properties were generated using the CDK toolkit. All properties were selected to enable the prediction of the Lipinski Rule-of-Five profile or ‘druglikeness’ for each ligand. For more info on each category see the help pages.

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Hydrogen bond acceptors 14
Hydrogen bond donors 8
Rotatable bonds 5
Topological polar surface area 225.06
Molecular weight 578.52
XLogP -0.15
No. Lipinski's rules broken 3
SMILES / InChI / InChIKey
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SMILES / InChI / InChIKey

SMILES (Simplified Molecular Input Line Entry Specification) A specification for unambiguously describing the structure of chemical molecules using short ASCII strings. Canonical SMILES specify a unique representation of the 2D structure without chiral or isotopic specifications. Isomeric SMILES include chiral specification and isotopes.

Standard InChI (IUPAC International Chemical Identifier) and InChIKey InChI is a non-proprietary, standard, textual identifier for chemical substances designed to facilitate linking of information and database searching. An InChIKey is a simplified version of a full InChI, designed for easier web searching.

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Canonical SMILES C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=CC3=C(C(=C2)O)C(=O)C(=C(C4=CC=C(C=C4)O)O3)O[C@H]5[C@@H]([C@@H]([C@H]([C@H](C)O5)O)O)O)O)O)O
Isomeric SMILES C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=CC(=C3C(=C2)OC(=C(C3=O)O[C@H]4[C@@H]([C@@H]([C@H]([C@@H](O4)C)O)O)O)C5=CC=C(C=C5)O)O)O)O)O
InChI InChI=1S/C27H30O14/c1-9-17(30)20(33)22(35)26(37-9)39-13-7-14(29)16-15(8-13)40-24(11-3-5-12(28)6-4-11)25(19(16)32)41-27-23(36)21(34)18(31)10(2)38-27/h3-10,17-18,20-23,26-31,33-36H,1-2H3/t9-,10-,17-,18-,20+,21+,22+,23+,26-,27-/m0/s1
InChI Key PUPKKEQDLNREIM-QNSQPKOQSA-N
Classification Click here for help
Compound class Natural product or derivative
IUPAC Name Click here for help
5-hydroxy-2-(4-hydroxyphenyl)-3,7-bis[[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy]chromen-4-one
Synonyms Click here for help
kaempferol 3,7-dirhamnoside | lespedin | lespenefril
Database Links Click here for help
ChEMBL Ligand CHEMBL251766
GtoPdb PubChem SID 491300059
PubChem CID 5486199
Search Google for chemical match using the InChIKey PUPKKEQDLNREIM-QNSQPKOQSA-N
Search Google for chemicals with the same backbone PUPKKEQDLNREIM
UniChem Compound Search for chemical match using the InChIKey PUPKKEQDLNREIM-QNSQPKOQSA-N
UniChem Connectivity Search for chemical match using the InChIKey PUPKKEQDLNREIM-QNSQPKOQSA-N