declovanillobiocin   Click here for help

GtoPdb Ligand ID: 12128

Synonyms: novclobiocin 313
Comment: Declovanillobiocin is an aminocoumarin antibacterial compound isolated from the culture broth of a cloQ- mutant of the clorobiocin producer Streptomyces roseochromogenes [1]. The same study also identified isovanillobiocin and vanillobiocin.
2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 7
Hydrogen bond donors 5
Rotatable bonds 10
Topological polar surface area 199.01
Molecular weight 624.2
XLogP 3.89
No. Lipinski's rules broken 0
Click here for help
Canonical SMILES CO[C@@H]1[C@@H](OC(=O)c2ccc([nH]2)C)[C@@H](O)[C@@H](OC1(C)C)Oc1ccc2c(c1)oc(=O)c(c2O)NC(=O)c1ccc(c(c1)OC)O
Isomeric SMILES Cc1ccc([nH]1)C(=O)O[C@H]1[C@H]([C@@H](OC([C@@H]1OC)(C)C)Oc1cc2c(cc1)c(c(c(=O)o2)NC(=O)c1cc(c(cc1)O)OC)O)O
InChI InChI=1S/C31H32N2O12/c1-14-6-10-18(32-14)28(38)44-25-24(36)30(45-31(2,3)26(25)41-5)42-16-8-9-17-20(13-16)43-29(39)22(23(17)35)33-27(37)15-7-11-19(34)21(12-15)40-4/h6-13,24-26,30,32,34-36H,1-5H3,(H,33,37)/t24-,25+,26-,30-/m1/s1
Classification Click here for help
Compound class Natural product or derivative
IUPAC Name Click here for help
[(3R,4S,5R,6R)-5-hydroxy-6-[4-hydroxy-3-[(4-hydroxy-3-methoxybenzoyl)amino]-2-oxochromen-7-yl]oxy-3-methoxy-2,2-dimethyloxan-4-yl] 5-methyl-1H-pyrrole-2-carboxylate
Synonyms Click here for help
novclobiocin 313
Database Links Click here for help
Specialist databases
Antibiotic DB Antibiotic DB Database logo Declovanillobiocin
Other databases
CAS Registry No. 744218-20-0 (source: Scifinder)
ChEMBL Ligand CHEMBL1275888
GtoPdb PubChem SID 472319250
PubChem CID 54697399
Search Google for chemical match using the InChIKey JURYCYSCKRZQLD-YYZJCXNBSA-N
Search Google for chemicals with the same backbone JURYCYSCKRZQLD
UniChem Compound Search for chemical match using the InChIKey JURYCYSCKRZQLD-YYZJCXNBSA-N
UniChem Connectivity Search for chemical match using the InChIKey JURYCYSCKRZQLD-YYZJCXNBSA-N