naringenin [Ligand Id: 10298] activity data from GtoPdb and ChEMBL
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
| ChEMBL ligand: CHEMBL32571 |
|---|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Dipeptidyl peptidase IV in Pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3813] [UniProtKB: P22411] | ||||||||
| ChEMBL | Inhibition of porcine DPP4 after 30 mins by luminescence assay | B | 5.6 | pIC50 | 2500 | nM | IC50 | Eur J Med Chem (2018) 151: 145-157 [PMID:29609120] |
| Cav1.2/Voltage-gated L-type calcium channel alpha-1C subunit in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3762] [GtoPdb: 529] [UniProtKB: P22002] | ||||||||
| ChEMBL | Inhibition of Cav1.2 calcium current measured using whole cell patch clamp in rat Artery myocytes | F | 4 | pIC50 | 100000 | nM | IC50 | IC50 data for the L-type calcium channel extracted from a set of literature articles |
| TRPM3 in Human [GtoPdb: 495] [UniProtKB: Q9HCF6] | ||||||||
| GtoPdb | - | - | 5.2 | pIC50 | - | - | - |
Br J Pharmacol (2013) 168: 1835-50 [PMID:23190005]; Mol Pharmacol (2013) 84: 736-50 [PMID:24006495] |
| TAS2R39 in Human [GtoPdb: 675] [UniProtKB: P59534] | ||||||||
| GtoPdb | - | - | 4.48 | pEC50 | 32900 | nM | EC50 | J Agric Food Chem (2013) 61: 10454-66 [PMID:24117141] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
