compound 16a [Sharratt et al., 1994] [Ligand Id: 3107] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL160176
  • squalene synthase /Squalene synthetase in Rat [ChEMBL: CHEMBL3815] [GtoPdb: 645] [UniProtKB: Q02769]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
squalene synthase /Squalene synthetase in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3815] [GtoPdb: 645] [UniProtKB: Q02769]
ChEMBL In vitro inhibitory concentration against squalene synthase from male rat liver microsomes B 7.96 pIC50 11 nM IC50 Bioorg. Med. Chem. Lett. (1994) 4: 661-666
GtoPdb In vitro inhibitory concentration against squalene synthase from male rat liver microsomes - 7.96 pIC50 11 nM IC50 Bioorg Med Chem Lett (1994) 4: 661-666

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]