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ChEMBL ligand: CHEMBL289498 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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CCK1 receptor/Cholecystokinin A receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2871] [GtoPdb: 76] [UniProtKB: P30551] | ||||||||
GtoPdb | - | - | 6.6 | pIC50 | - | - | - | Proc Natl Acad Sci USA (1990) 87: 6728-32 [PMID:1975695] |
ChEMBL | Displacement of [125 I] CCK-8 from Cholecystokinin type A receptor of rat pancreas | B | 8.09 | pIC50 | 8.1 | nM | IC50 | J Med Chem (1989) 32: 13-16 [PMID:2909725] |
CCK2 receptor/Cholecystokinin B receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL298] [GtoPdb: 77] [UniProtKB: P32239] | ||||||||
ChEMBL | Displacement of [125 I] CCK-8 from Cholecystokinin type B receptor of guinea pig cerebral cortex | B | 8.15 | pIC50 | 7.1 | nM | IC50 | J Med Chem (1989) 32: 13-16 [PMID:2909725] |
ChEMBL | Displacement of [125I]-gastrin17 from CCK-B receptor (unknown origin) | B | 8.28 | pIC50 | 5.2 | nM | IC50 | Medchemcomm (2017) 8: 1561-1574 [PMID:30108868] |
GtoPdb | - | - | 8.4 | pIC50 | 3.98 | nM | IC50 | J Biol Chem (1993) 268: 8164-9 [PMID:7681836] |
ChEMBL | Displacement of 125 I-gastrin from gastrin receptor of guinea pig gastric glands | B | 8.51 | pIC50 | 3.1 | nM | IC50 | J Med Chem (1989) 32: 13-16 [PMID:2909725] |
CCK2 receptor/Cholecystokinin B receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3508] [GtoPdb: 77] [UniProtKB: P30553] | ||||||||
ChEMBL | Displacement of [125I]-BH-CCK-8 from CCK-B receptor in rat cerebral cortex plasma membrane after 1 hr by liquid scintillation counting method | B | 8.42 | pIC50 | 3.8 | nM | IC50 | Medchemcomm (2017) 8: 1561-1574 [PMID:30108868] |
ChEMBL data shown on this page come from version 32:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]