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ChEMBL ligand: CHEMBL482477 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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Peroxisome proliferator-activated receptor-γ/Peroxisome proliferator-activated receptor gamma in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL235] [GtoPdb: 595] [UniProtKB: P37231] | ||||||||
ChEMBL | Binding affinity to PPARgamma | B | 5.7 | pKd | 2000 | nM | Kd | J. Med. Chem. (2012) 55: 4027-4061 [PMID:22260081] |
GtoPdb | - | - | 6.3 | pIC50 | - | - | - |
Proc Natl Acad Sci USA (1997) 94: 4318-23 [PMID:9113987]; Cell (1995) 83: 813-9 [PMID:8521498]; Anal Biochem (1998) 257: 112-9 [PMID:9514791]; Cell Signal (2002) 14: 573-83 [PMID:11955950]; Biochem Biophys Res Commun (2005) 337: 521-5 [PMID:16198309] |
TRPA1/Transient receptor potential cation channel subfamily A member 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL6007] [GtoPdb: 485] [UniProtKB: O75762] | ||||||||
ChEMBL | Activation of TRPA1 channel | B | 5.25 | pEC50 | 5600 | nM | EC50 | J. Med. Chem. (2010) 53: 5085-5107 [PMID:20356305] |
ChEMBL data shown on this page come from version 31:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]