clometocillin   Click here for help

GtoPdb Ligand ID: 12294

Synonyms: clometacillin | clomethacillin
Compound class: Synthetic organic
Comment: Clometocillin is a penicillin belonging to the β-lactam class of antibacterial compounds.
2D Structure
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2D Structure

An image of the ligand's 2D structure. For small molecules with SMILES these are drawn using the NCI/CADD Chemical Identifier Resolver. Click on the image to access the chemical structure search tool with the ligand pre-loaded in the structure editor. For other types of ligands, e.g. longer nucleotides and peptides, a manually drawn representation of the molecule may be provided.

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Physico-chemical Properties
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Physico-chemical Properties

Calculated molecular properties are available for small molecules and natural products (not peptides). Properties were generated using the CDK toolkit. All properties were selected to enable the prediction of the Lipinski Rule-of-Five profile or ‘druglikeness’ for each ligand. For more info on each category see the help pages.

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Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 121.24
Molecular weight 432.03
XLogP 2.26
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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SMILES / InChI / InChIKey

SMILES (Simplified Molecular Input Line Entry Specification) A specification for unambiguously describing the structure of chemical molecules using short ASCII strings. Canonical SMILES specify a unique representation of the 2D structure without chiral or isotopic specifications. Isomeric SMILES include chiral specification and isotopes.

Standard InChI (IUPAC International Chemical Identifier) and InChIKey InChI is a non-proprietary, standard, textual identifier for chemical substances designed to facilitate linking of information and database searching. An InChIKey is a simplified version of a full InChI, designed for easier web searching.

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Canonical SMILES COC(c1ccc(c(c1)Cl)Cl)C(=O)N[C@@H]1C(=O)N2[C@@H]1SC([C@@H]2C(=O)O)(C)C
Isomeric SMILES CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)C(c1cc(c(cc1)Cl)Cl)OC)C(=O)O)C
InChI InChI=1S/C17H18Cl2N2O5S/c1-17(2)12(16(24)25)21-14(23)10(15(21)27-17)20-13(22)11(26-3)7-4-5-8(18)9(19)6-7/h4-6,10-12,15H,1-3H3,(H,20,22)(H,24,25)/t10-,11?,12+,15-/m1/s1
InChI Key JKXQBIZCQJLVOS-GSNLGQFWSA-N
Classification Click here for help
Compound class Synthetic organic
IUPAC Name Click here for help
(2S,5R,6R)-6-[[2-(3,4-dichlorophenyl)-2-methoxyacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
International Nonproprietary Names Click here for help
INN number INN
1326 clometocillin
Synonyms Click here for help
clometacillin | clomethacillin
Database Links Click here for help
Specialist databases
Antibiotic DB Antibiotic DB Database logo Clometocillin, clometacillin
Other databases
CAS Registry No. 1926-49-4 (source: Scifinder)
ChEBI CHEBI:131732
ChEMBL Ligand CHEMBL2106548
DrugBank Ligand DB13686
DrugCentral Ligand 699
GtoPdb PubChem SID 479821085
PubChem CID 71807
Search Google for chemical match using the InChIKey JKXQBIZCQJLVOS-GSNLGQFWSA-N
Search Google for chemicals with the same backbone JKXQBIZCQJLVOS
Search PubMed clinical trials clometocillin
Search PubMed titles clometocillin
Search PubMed titles/abstracts clometocillin
UniChem Compound Search for chemical match using the InChIKey JKXQBIZCQJLVOS-GSNLGQFWSA-N
UniChem Connectivity Search for chemical match using the InChIKey JKXQBIZCQJLVOS-GSNLGQFWSA-N