Synonyms: Atabrine® | quinacrine
Compound class:
Synthetic organic
Comment: Mepacrine is an acridine derivative with antiprotozoal activity. Historically used as an antimalarial drug it is now used off-license as an immunomodulatory agent.
The Malaria tab on this ligand page provides additional curator comments of relevance to the Guide to MALARIA PHARMACOLOGY. |
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Classification ![]() |
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Compound class | Synthetic organic |
Ligand families/groups | Antimalarial ligands |
IUPAC Name ![]() |
N'-(6-chloro-2-methoxyacridin-9-yl)-N,N-diethylpentane-1,4-diamine |
International Nonproprietary Names ![]() |
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INN number | INN |
396 | mepacrine |
Synonyms ![]() |
Atabrine® | quinacrine |
Database Links ![]() |
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Specialist databases | |
Reactome Drug
![]() |
R-ALL-9695421 |
Reactome Reaction
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R-HSA-9695415 |
Other databases | |
CAS Registry No. | 83-89-6 (source: Scifinder) |
ChEBI | CHEBI:8711 |
ChEMBL Ligand | CHEMBL7568 |
DrugBank Ligand | DB01103 |
DrugCentral Ligand | 2338 |
GtoPdb PubChem SID | 381118882 |
PubChem CID | 237 |
RCSB PDB Ligand | QUN |
Search Google for chemical match using the InChIKey | GPKJTRJOBQGKQK-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | GPKJTRJOBQGKQK |
Search PubMed clinical trials | mepacrine |
Search PubMed titles | mepacrine |
Search PubMed titles/abstracts | mepacrine |
UniChem Compound Search for chemical match using the InChIKey | GPKJTRJOBQGKQK-UHFFFAOYSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | GPKJTRJOBQGKQK-UHFFFAOYSA-N |
Wikipedia | Mepacrine |