Synonyms: LY-3473329 | LY3473329
Compound class:
Synthetic organic
Comment: Muvalaplin (LY3473329) is an orally bioavailable small molecule that disrupts the binding of apolipoprotein(a) to apolipoprotein B100, thus blocking the formation of lipoprotein(a) [1]. It was designed to treat atherosclerotic disease. Muvalaplin does not bind to plasminogen.
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Classification | |
Compound class | Synthetic organic |
IUPAC Name |
(2S)-3-[3-[[bis[[3-[(2S)-2-carboxy-2-[(3R)-pyrrolidin-3-yl]ethyl]phenyl]methyl]amino]methyl]phenyl]-2-[(3R)-pyrrolidin-3-yl]propanoic acid |
International Nonproprietary Names | |
INN number | INN |
12607 | muvalaplin |
Synonyms |
LY-3473329 | LY3473329 |
Database Links | |
CAS Registry No. | 2565656-70-2 (source: WHO INN record) |
ChEMBL Ligand | CHEMBL4802585 |
GtoPdb PubChem SID | 485206060 |
PubChem CID | 155369486 |
Search Google for chemical match using the InChIKey | BRLGERLDHZRETI-BGBFCPIGSA-N |
Search Google for chemicals with the same backbone | BRLGERLDHZRETI |
Search PubMed clinical trials | muvalaplin |
Search PubMed titles | muvalaplin |
Search PubMed titles/abstracts | muvalaplin |
UniChem Compound Search for chemical match using the InChIKey | BRLGERLDHZRETI-BGBFCPIGSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | BRLGERLDHZRETI-BGBFCPIGSA-N |