FGF-19   Click here for help

GtoPdb Ligand ID: 11545

Synonyms: fibroblast growth factor 19
Comment: FGF-19 is a fibroblast growth factor that mediates a wide range of mitogenic and cell survival activities. It is one of the endogenous ligands for fibroblast growth factor receptor 4 (FGFR4) [2]. FGF-19 is a major player in the gut-liver axis that maintains bile acid homeostasis, its expression is induced in the liver under cholestatic and cirrhotic conditions, and it is implicated in the development of hepatocellular carcinoma (HCC).
Species: Human
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Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Synonyms Click here for help
fibroblast growth factor 19
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
FGF19 fibroblast growth factor 19 Human fibroblast growth factor 19 precursor -
Database Links Click here for help
Ensembl Gene ENSG00000162344 (Hs)
Entrez Gene 9965 (Hs)
GtoPdb PubChem SID 441604917
Human Protein Atlas ENSG00000162344 (Hs)
OMIM 603891 (Hs)
RefSeq Nucleotide NM_005117 (Hs)
RefSeq Protein NP_005108 (Hs)
UniProtKB O95750 (Hs)