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Synonyms: AMG-162 | M05BX04 | Prolia® | Xgeva®
denosumab is an approved drug (FDA and EMA (2010))
Compound class: Antibody
Comment: Denosumab suppresses the activity of RANK ligand (RANKL), which normally promotes bone removal and resorption, but which becomes over active in many bone loss diseases.
Denosumab is produced from CHO cells stably expressing recombinant antibody component proteins .
View more information in the IUPHAR Pharmacology Education Project: denosumab
|Approved drug?||Yes (FDA and EMA (2010))|
|International Nonproprietary Names|
|AMG-162 | M05BX04 | Prolia® | Xgeva®|
|GtoPdb PubChem SID||178103468|
|Search PubMed clinical trials||denosumab|
|Search PubMed titles||denosumab|
|Search PubMed titles/abstracts||denosumab|