Ligand id: 6886

Name: denosumab

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Compound class Antibody
Approved drug? Yes (FDA and EMA (2010))
International Nonproprietary Names
INN number INN
8653 denosumab
AMG-162 | M05BX04 | Prolia® | Xgeva®
Denosumab suppresses the activity of RANK ligand (RANKL), which normally promotes bone removal and resorption, but which becomes over active in many bone loss diseases.
Denosumab is produced from CHO cells stably expressing recombinant antibody component proteins [1].
Database Links
Specialist databases
IMGT/mAb-DB 249
Other databases
GtoPdb PubChem SID 178103468
PubChem SID 178103468
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Wikipedia Denosumab