RANK ligand

Ligand id: 5066

Name: RANK ligand

Species: Human

Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups CD molecules (ligands)Tumor necrosis factor superfamily ligands
receptor activator of nuclear factor κB ligand | osteoclast differentiation factor (ODF) | osteoprotegerin ligand | TNFSF11
RANK ligand (TNFSF11) is a member of the tumor necrosis factor (TNF) cytokine family. It can exist in both membrane-bound and soluble forms. It is a key factor for osteoclast differentiation and activation. Osteoprotegerin acts as a decoy receptor for RANK ligand.
Gene symbol Gene name Species Precursor protein name Synonyms
TNFSF11 TNF superfamily member 11 Human prepro-tumor necrosis factor ligand superfamily member 11 CD254, ODF, OPGL, RANKL, TRANCE, tumor necrosis factor (ligand) superfamily, member 11, tumor necrosis factor superfamily member 11
Database Links
DrugBank Target O14788 (Hs)
Ensembl Gene ENSG00000120659 (Hs)
GtoPdb PubChem SID 178101759
Human Protein Atlas ENSG00000120659 (Hs)
Immunopaedia Search RANK ligand
UniProtKB O14788 (Hs)
Wikipedia RANKL