RANK ligand   

GtoPdb Ligand ID: 5066

Synonyms: receptor activator of nuclear factor κB ligand | osteoclast differentiation factor (ODF) | osteoprotegerin ligand | TNFSF11
Comment: RANK ligand (TNFSF11) is a member of the tumor necrosis factor (TNF) cytokine family. It can exist in both membrane-bound and soluble forms. It is a key factor for osteoclast differentiation and activation. Osteoprotegerin acts as a decoy receptor for RANK ligand.
Species: Human
Classification
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups CD molecules (ligands)Tumor necrosis factor superfamily ligands
Synonyms
receptor activator of nuclear factor κB ligand | osteoclast differentiation factor (ODF) | osteoprotegerin ligand | TNFSF11
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
TNFSF11 TNF superfamily member 11 Human prepro-tumor necrosis factor ligand superfamily member 11 CD254, ODF, OPGL, RANKL, TRANCE, tumor necrosis factor (ligand) superfamily, member 11, tumor necrosis factor superfamily member 11
Database Links
CATH/Gene3D 2.60.120.40
DrugBank Target O14788 (Hs)
Ensembl Gene ENSG00000120659 (Hs)
GtoPdb PubChem SID 178101759
Human Protein Atlas ENSG00000120659 (Hs)
Immunopaedia Search RANK ligand
UniProtKB O14788 (Hs)
Wikipedia RANKL