nogapendekin alfa   Click here for help

GtoPdb Ligand ID: 11594

Synonyms: IL15 D72
Comment: Inogapendekin alfa is recombinant human IL-15 with an amino acid substitution (Asn72Asp/N72D) that enhances its agonist activity at the IL-15Rβγc complex. IL-15N72D increases biological activity by 4-5-fold compared to the wild type cytokine. Inogapendekin alfa is synthesised in tandem with inbakicept to generate the clinical stage IL-15 superagonist complex ALT-803.
Classification Click here for help
Compound class Peptide or derivative
International Nonproprietary Names Click here for help
INN number INN
11157 nogapendekin alfa
Synonyms Click here for help
IL15 D72
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 983
Other databases
GtoPdb PubChem SID 442878628
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