benralizumab [Ligand Id: 7674] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1742991 (Fasenra, BIW-8405, MEDI-563, Benralizumab)
  • Interleukin 5 receptor, α subunit in Human [GtoPdb: 1706] [UniProtKB: Q01344]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Interleukin 5 receptor, α subunit in Human [GtoPdb: 1706] [UniProtKB: Q01344]
GtoPdb - - 8.67 pKd 2.13 nM Kd US8501176. Methods of reducing eosinophil levels. (2013)

ChEMBL data shown on this page come from version 27:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]