ChEMBL ligand: CHEMBL539 (Acetasol, Acetic, Acetic acid, Acetic Acid, Acetic acid, diluted, Acetic acid glacial, Acetic acid, glacial, Acetic acid,glacial, Acetic Acid, Glacial, Aceticum acidum, Acetopyrine, Acidum aceticum, Acidum aceticum glaciale, Aci-jel, Acopyrine, Antipyrine acetylsalicylate, Distilled vinegar, E-260, E260, Earcalm, FEMA NO. 2006, Glacial acetic acid, INS-260, INS NO.260, NSC-111201, NSC-112209, NSC-115870, NSC-127175, NSC-132953, NSC-406306, Orlex, Orthoacetic acid, Pyrosal, Vinegar, Vinegar acid, Vosol)
FFA3 receptor/Free fatty acid receptor 3 in Human [ChEMBL: CHEMBL5201] [GtoPdb: 227] [UniProtKB: O14843] There should be some charts here, you may need to enable JavaScript!
FYN proto-oncogene, Src family tyrosine kinase/Tyrosine-protein kinase FYN in Human [ChEMBL: CHEMBL1841] [GtoPdb: 2026] [UniProtKB: P06241] There should be some charts here, you may need to enable JavaScript!
LCK proto-oncogene, Src family tyrosine kinase/Tyrosine-protein kinase LCK in Human [ChEMBL: CHEMBL258] [GtoPdb: 2053] [UniProtKB: P06239] There should be some charts here, you may need to enable JavaScript!
FFA2 receptor in Human [GtoPdb: 226] [UniProtKB: O15552] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
FFA3 receptor/Free fatty acid receptor 3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5201] [GtoPdb: 227] [UniProtKB: O14843]
GtoPdb	-	-	3.9	pEC50	-	-	-	J Biol Chem (2003) 278: 11312-9 [PMID:12496283]; J Biol Chem (2003) 278: 25481-9 [PMID:12711604]; Proc Natl Acad Sci USA (2004) 101: 1045-50 [PMID:14722361]; J Biol Chem (2011) 286: 10628-40 [PMID:21220428]
ChEMBL	Agonist activity at human GPCR41 transfected in HEK293 cells assessed as [35S]GTPgammaS binding by scintillation counting method	F	4.92	pEC50	12000	nM	EC50	J Med Chem (2018) 61: 47-61 [PMID:28745893]
FYN proto-oncogene, Src family tyrosine kinase/Tyrosine-protein kinase FYN in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1841] [GtoPdb: 2026] [UniProtKB: P06241]
ChEMBL	Dissociation constant for binding to SH2 domain of Fyn protein kinase	B	6.05	pKd	900	nM	Kd	J Med Chem (1999) 42: 784-787 [PMID:10072676]
LCK proto-oncogene, Src family tyrosine kinase/Tyrosine-protein kinase LCK in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL258] [GtoPdb: 2053] [UniProtKB: P06239]
ChEMBL	Dissociation constant for binding to SH2 domain of p56 lck tyrosine kinase	B	5.89	pKd	1300	nM	Kd	J Med Chem (1999) 42: 784-787 [PMID:10072676]
ChEMBL	Dissociation constant for binding to SH2 domain of p56 lck tyrosine kinase	B	6.19	pKd	640	nM	Kd	J Med Chem (1999) 42: 784-787 [PMID:10072676]
FFA2 receptor in Human [GtoPdb: 226] [UniProtKB: O15552]
GtoPdb	-	-	4.6	pEC50	-	-	-	J Biol Chem (2003) 278: 11312-9 [PMID:12496283]; Biochem Biophys Res Commun (2003) 303: 1047-52 [PMID:12684041]; J Biol Chem (2003) 278: 25481-9 [PMID:12711604]; J Biol Chem (2011) 286: 10628-40 [PMID:21220428]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]