ChEMBL ligand: CHEMBL1121 (Cck-8, Cck c-terminal octapeptide, Cholecystokinin, Cholecystokinin c-terminal octapeptide, Kinevac, Pancreozymin, Sincalide, SQ 19844, SQ-19844)
CCK1 receptor/Cholecystokinin A receptor in Human [ChEMBL: CHEMBL1901] [GtoPdb: 76] [UniProtKB: P32238] CCK1 receptor/Cholecystokinin A receptor in Rat [ChEMBL: CHEMBL2871] [GtoPdb: 76] [UniProtKB: P30551] Cholecystokinin A receptor in Guinea pig [ChEMBL: CHEMBL3501] [UniProtKB: Q63931] There should be some charts here, you may need to enable JavaScript!
CCK2 receptor/Cholecystokinin B receptor in Human [ChEMBL: CHEMBL298] [GtoPdb: 77] [UniProtKB: P32239] CCK2 receptor/Cholecystokinin B receptor in Mouse [ChEMBL: CHEMBL2854] [GtoPdb: 77] [UniProtKB: P56481] CCK2 receptor/Cholecystokinin B receptor in Rat [ChEMBL: CHEMBL3508] [GtoPdb: 77] [UniProtKB: P30553] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
CCK1 receptor/Cholecystokinin A receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1901] [GtoPdb: 76] [UniProtKB: P32238]
ChEMBL	Displacement of radiolabeled CCK-8s from human CCK1 receptor	B	9.55	pKi	0.28	nM	Ki	J. Med. Chem. (2008) 51: 7094-7098 [PMID:18983139]
ChEMBL	In vitro for binding affinity against human cholecystokinin type A receptor.	B	8.88	pIC50	1.32	nM	IC50	J. Med. Chem. (1997) 40: 2706-2725 [PMID:9276016]
ChEMBL	Binding affinity against human Cholecystokinin type A receptor by displacement of [125I]CCK-8	B	8.88	pIC50	1.32	nM	IC50	J. Med. Chem. (1996) 39: 2655-2658 [PMID:8709093]
ChEMBL	Binding affinity against human Cholecystokinin type A receptor in membrane preparation isolated from CHO-K1 cells stably transfected with cDNA of human CCK-A using [125I]-Bolton-Hunter CCK-8 as radioligand	B	8.88	pIC50	1.32	nM	IC50	J. Med. Chem. (1996) 39: 3030-3034 [PMID:8709137]
ChEMBL	Tested for the 50% displacement of [125I]CCK-8 from membrane preparation isolated from CHO-K1 cells stably transfected with the cDNA of human Cholecystokinin type A receptor	B	8.9	pIC50	1.26	nM	IC50	Bioorg. Med. Chem. Lett. (1997) 7: 511-514
ChEMBL	Compound was tested in vitro for its ability to displace [125I]Bolton-Hunter CCK-8 from membrane preparation isolated from CHO-KI cells stably transfected with cDNA of human Cholecystokinin type A receptor	B	9.2	pIC50	0.63	nM	IC50	J. Med. Chem. (1996) 39: 5236-5245 [PMID:8978852]
ChEMBL	Concentration required to displace [125I]Bolton-Hunter CCK-8 from human Cholecystokinin type A receptor stably expressed in CHO-K1 cells	B	9.2	pIC50	0.63	nM	IC50	J. Med. Chem. (1996) 39: 562-569 [PMID:8558528]
ChEMBL	Displacement of CCK-8 from CHO cell membranes expressing human Cholecystokinin type A receptor	B	9.4	pIC50	0.4	nM	IC50	J. Med. Chem. (1995) 38: 207-211 [PMID:7837233]
ChEMBL	In vitro displacement of [125I]BH-CCK-8 from cDNA of human Cholecystokinin type A receptor expressed in CHO-K1 cells	B	9.41	pIC50	0.39	nM	IC50	J. Med. Chem. (1995) 38: 3384-3390 [PMID:7650691]
ChEMBL	Displacement of radiolabeled CCK-8s from human CCK1 receptor	B	9.43	pIC50	0.37	nM	IC50	J. Med. Chem. (2008) 51: 7094-7098 [PMID:18983139]
ChEMBL	Displacement of [125I]CCK-8s from human recombinant CCK-A receptor expressed in CHO cells	B	9.89	pIC50	0.13	nM	IC50	Bioorg. Med. Chem. (2016) 24: 1793-1810 [PMID:26988801]
ChEMBL	Displacement of [125I]CCK-8s from human recombinant CCK1 receptor expressed in CHO cells measured after 60 mins by scintillation counting method	B	9.89	pIC50	0.13	nM	IC50	Bioorg Med Chem (2017) 25: 471-482 [PMID:27876250]
ChEMBL	Displacement of [125I]-CCK-8 from human CCK1R expressed in human 1321N1 cell membranes after 2 hrs by SPA assay	B	9.95	pIC50	0.11	nM	IC50	J Med Chem (2019) 62: 1407-1419 [PMID:30624060]
ChEMBL	Antagonist activity at CCK1 receptor expressed in HEK 293 cells assessed as accumulation of [3H]inositol phosphates by PI assay	F	7.55	pEC50	28.18	nM	EC50	J. Med. Chem. (2006) 49: 2868-2875 [PMID:16686530]
ChEMBL	Antagonist activity at CCK1 receptor expressed in HEK 293 cells assessed as accumulation of [3H]inositol phosphates by PI assay	F	7.55	pEC50	28	nM	EC50	J. Med. Chem. (2006) 49: 2868-2875 [PMID:16686530]
ChEMBL	Compound was evaluated for the [Ca2+] mobilization innstably transfected CHO-K1 cell lines expressing human Cholecystokinin type A receptor	B	10	pEC50	0.1	nM	EC50	J. Med. Chem. (1995) 38: 3384-3390 [PMID:7650691]
ChEMBL	Agonist activity at human CCK1R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assay	F	10.36	pEC50	0.04	nM	EC50	J Med Chem (2019) 62: 1407-1419 [PMID:30624060]
CCK1 receptor/Cholecystokinin A receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2871] [GtoPdb: 76] [UniProtKB: P30551]
ChEMBL	Evaluated for binding affinity measured by inhibiting [3H]Boc[Nle28,31]CCK27-33 specific binding to Cholecystokinin receptor in rat pancreas membranes at a KD concentration of 4.4 nM	B	8.06	pKi	8.71	nM	Ki	J. Med. Chem. (1987) 30: 962-968 [PMID:2438407]
ChEMBL	Inhibition of [3H]pCCK-8 specific binding to Cholecystokinin type A receptor of rat pancreas	B	9.28	pKi	0.52	nM	Ki	J. Med. Chem. (1997) 40: 3402-3407 [PMID:9341915]
ChEMBL	Binding affinity for Cholecystokinin type A receptor using [125I]BH-CCK-8 in rat pancreatic tissue	B	10.05	pKi	0.09	nM	Ki	J. Med. Chem. (1997) 40: 4302-4307 [PMID:9435899]
ChEMBL	Inhibition of [125I]BH-CCK-8 binding to Cholecystokinin type A receptor of rat pancreatic tissue	B	10.05	pKi	0.09	nM	Ki	J. Med. Chem. (2000) 43: 2350-2355 [PMID:10882360]
GtoPdb	-	-	7.2	pIC50	-	-	-	Proc Natl Acad Sci USA (1990) 87: 6728-32 [PMID:1975695]
ChEMBL	Tested for the inhibition of specific [3H]propionyl-CCK-8 binding to rat pancreas membrane(CCK-A)	B	8.97	pIC50	1.08	nM	IC50	Bioorg. Med. Chem. Lett. (1997) 7: 855-860
ChEMBL	Binding affinity by competitive inhibition of the radioligand [3H]pCCK-8 at Cholecystokinin type A receptor from rat pancreas	B	8.98	pIC50	1.04	nM	IC50	J. Med. Chem. (1999) 42: 4659-4668 [PMID:10579828]
ChEMBL	Inhibition of [3H]pCCK-8 binding to cholecystokinin type A receptor of rat pancreas	B	8.98	pIC50	1.04	nM	IC50	J. Med. Chem. (2001) 44: 4196-4206 [PMID:11708921]
ChEMBL	Inhibition of [3H]-pCCK-8 binding to Cholecystokinin type A receptor of rat pancreas homogenates	B	8.98	pIC50	1.04	nM	IC50	J. Med. Chem. (2004) 47: 5318-5329 [PMID:15456276]
ChEMBL	Compound was evaluated for the binding affinity towards rat pancreatic Cholecystokinin type A receptor	B	9	pIC50	1	nM	IC50	Bioorg. Med. Chem. Lett. (2000) 10: 1245-1248 [PMID:10866391]
ChEMBL	Displacement of 125I]-D-Tyr-Gly-[(Nle28,31)CCK-26-33] from rat cell membrane Cholecystokinin type A receptor	B	9.1	pIC50	0.8	nM	IC50	Bioorg. Med. Chem. Lett. (1998) 8: 3127-3132 [PMID:9873689]
ChEMBL	Concentration required to inhibit by 50% specific binding of [125I](BH)-CCK-8 to cholecystokinin type A receptor in rat pancreatic acini	B	9.3	pIC50	0.5	nM	IC50	J. Med. Chem. (1992) 35: 28-38 [PMID:1732532]
GtoPdb	-	-	9.9	pIC50	-	-	-	Proc Natl Acad Sci USA (1990) 87: 6728-32 [PMID:1975695]
ChEMBL	Inhibition of [125I]- Bolton-Hunter CCK-26-33 binding to Cholecystokinin type A receptor of rat pancreas	B	10	pIC50	0.1	nM	IC50	Bioorg. Med. Chem. Lett. (1993) 3: 889-894
ChEMBL	Half-maximal inhibition of specific binding of [125I]bolton hunter CCK-8 to rat pancreas cholecystokinin type A receptor	B	10	pIC50	0.1	nM	IC50	J. Med. Chem. (1991) 34: 404-414 [PMID:1671419]
ChEMBL	Evaluated for inhibition of cholecystokinin type A receptor by displacing [125I]bolton hunter CCK-8 radioligand in the rat pancreas	B	10	pIC50	0.1	nM	IC50	J. Med. Chem. (1992) 35: 2573-2581 [PMID:1635058]
ChEMBL	Inhibition of binding of [125I]Bolton-Hunter labeled CCK-8 to cholecystokinin type A receptor in the rat pancreas.	B	10	pIC50	0.1	nM	IC50	J. Med. Chem. (1993) 36: 552-565 [PMID:7684452]
Cholecystokinin A receptor in Guinea pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3501] [UniProtKB: Q63931]
ChEMBL	Displacement of [3H]-pCCK-8 from cholecystokinin-A receptor in guinea pig pancreatic membrane	B	9.15	pKi	0.7	nM	Ki	J. Med. Chem. (1993) 36: 166-172 [PMID:8421283]
ChEMBL	Compound was tested for binding affinity against CCK1 (cholecystokinin) receptor on guinea pig pancreatic membranes	B	9.15	pKi	0.7	nM	Ki	J. Med. Chem. (2000) 43: 3614-3623 [PMID:11020275]
ChEMBL	The compound was tested for the inhibition of [3H]propionyl specific binding to CCK-8 receptor of guinea pig pancreatic membrane	B	9.19	pKi	0.64	nM	Ki	J. Med. Chem. (1989) 32: 445-449 [PMID:2464062]
ChEMBL	Tested for the inhibition of [3H]pCCK-8 binding to Cholecystokinin type A receptor in pancreatic membranes of guinea-pig	B	9.19	pKi	0.64	nM	Ki	Bioorg. Med. Chem. Lett. (1993) 3: 847-850
ChEMBL	Displacement of 0.1 nM [3H]pCCK-8 from guinea pig pancreatic membranes	B	9.19	pKi	0.64	nM	Ki	J. Med. Chem. (1989) 32: 1184-1190 [PMID:2724293]
ChEMBL	Ability to displace 1 nM [3H]pCCK-8 from Cholecystokinin type A receptor in guinea pig pancreatic membranes	B	9.22	pKi	0.6	nM	Ki	Bioorg. Med. Chem. Lett. (2004) 14: 369-372 [PMID:14698161]
ChEMBL	Inhibition of [3H]pCCK-8 binding to Cholecystokinin type A receptor of Guinea pig pancreatic membranes	B	9.55	pKi	0.28	nM	Ki	J. Med. Chem. (1997) 40: 647-658 [PMID:9057851]
ChEMBL	The compound was tested for the inhibition of [3H]propionyl specific binding to CCK-8 receptor of guinea pig brain	B	9.55	pKi	0.28	nM	Ki	J. Med. Chem. (1989) 32: 445-449 [PMID:2464062]
ChEMBL	Displacement of [125I]BH-CCK-8 from Cholecystokinin type A receptor in guinea pig pancreas	B	9.4	pIC50	0.4	nM	IC50	J. Med. Chem. (1990) 33: 2950-2952 [PMID:1700123]
ChEMBL	Displacement of [125I]Bolton-Hunter-CCK-8 from guinea pig pancreas Cholecystokinin type A receptor	B	9.55	pIC50	0.28	nM	IC50	Bioorg. Med. Chem. Lett. (1993) 3: 855-860
CCK2 receptor/Cholecystokinin B receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL298] [GtoPdb: 77] [UniProtKB: P32239]
ChEMBL	The compound was evaluated for the inhibition of binding of [3H]-PD 140376 to Cholecystokinin type B receptor in guinea pig cortex.	B	9.19	pKi	0.65	nM	Ki	Bioorg. Med. Chem. Lett. (1993) 3: 885-888
ChEMBL	Inhibition of [3H]pCCK-8 binding to Guinea pig cortex membrane Cholecystokinin type B receptor	B	9.19	pKi	0.64	nM	Ki	J. Med. Chem. (1997) 40: 647-658 [PMID:9057851]
ChEMBL	Displacement of radiolabeled CCK-8s from human CCK2 receptor	B	9.43	pKi	0.37	nM	Ki	J. Med. Chem. (2008) 51: 7094-7098 [PMID:18983139]
ChEMBL	Displacement of [3H]pCCK-8 from cholecystokinin type B receptor in guinea pig brain membrane	B	9.52	pKi	0.3	nM	Ki	J. Med. Chem. (1993) 36: 166-172 [PMID:8421283]
ChEMBL	Binding affinity against cholecystokinin type B receptor on guinea pig cortex.	B	9.52	pKi	0.3	nM	Ki	J. Med. Chem. (2000) 43: 3614-3623 [PMID:11020275]
ChEMBL	Inhibitory activity against Cholecystokinin type B receptor	B	9.52	pKi	0.3	nM	Ki	Bioorg. Med. Chem. Lett. (1993) 3: 799-802
ChEMBL	Tested for the inhibition of [3H]pCCK-8 binding to Cholecystokinin type B receptor in guinea pig brain	B	9.55	pKi	0.28	nM	Ki	Bioorg. Med. Chem. Lett. (1993) 3: 847-850
ChEMBL	Displacement of 0.2 nM [3H]pCCK-8 from guinea pig brain membranes	B	9.55	pKi	0.28	nM	Ki	J. Med. Chem. (1989) 32: 1184-1190 [PMID:2724293]
ChEMBL	Displacement of [125I]BH-CCK-8 from Cholecystokinin type B receptor of guinea pig cortex	B	8.09	pIC50	8.2	nM	IC50	J. Med. Chem. (1990) 33: 2950-2952 [PMID:1700123]
ChEMBL	Displacement of [125I]Bolton-Hunter-CCK-8 from guinea pig cortex Cholecystokinin type B receptor	B	8.8	pIC50	1.6	nM	IC50	Bioorg. Med. Chem. Lett. (1993) 3: 855-860
ChEMBL	Displacement of radiolabeled CCK-8s from human CCK2 receptor	B	9.04	pIC50	0.92	nM	IC50	J. Med. Chem. (2008) 51: 7094-7098 [PMID:18983139]
ChEMBL	Binding affinity against human Cholecystokinin type B receptor in CHO-K1 cells using [125I]-Bolton-Hunter CCK-8 as radioligand	B	9.46	pIC50	0.35	nM	IC50	J. Med. Chem. (1996) 39: 3030-3034 [PMID:8709137]
ChEMBL	In vitro for binding affinity against human cholecystokinin type B receptor.	B	9.46	pIC50	0.35	nM	IC50	J. Med. Chem. (1997) 40: 2706-2725 [PMID:9276016]
ChEMBL	Tested for 50% displacement of [125I]CCK-8 from membrane preparation isolated from CHO-K1 cells stably transfected with the cDNA of human Cholecystokinin type B receptor	B	9.5	pIC50	0.32	nM	IC50	Bioorg. Med. Chem. Lett. (1997) 7: 511-514
ChEMBL	Compound was tested in vitro for its ability to displace [125I]Bolton-Hunter CCK-8 from membrane preparation isolated from CHO-KI cells stably transfected with cDNA of human Cholecystokinin type B receptor	B	9.5	pIC50	0.32	nM	IC50	J. Med. Chem. (1996) 39: 5236-5245 [PMID:8978852]
ChEMBL	Concentration required to displace [125I]Bolton-Hunter CCK-8 from human Cholecystokinin type B receptor stably expressed in CHO-K1 cells	B	9.5	pIC50	0.32	nM	IC50	J. Med. Chem. (1996) 39: 562-569 [PMID:8558528]
ChEMBL	Displacement of CCK-8 from human Cholecystokinin type B receptor expressing CHO cell membranes	B	9.5	pIC50	0.32	nM	IC50	J. Med. Chem. (1995) 38: 207-211 [PMID:7837233]
ChEMBL	In vitro displacement of [125I]BH-CCK-8 from cDNA of human Cholecystokinin type B receptor expressed in CHO-K1 cells	B	9.5	pIC50	0.32	nM	IC50	J. Med. Chem. (1995) 38: 3384-3390 [PMID:7650691]
ChEMBL	Displacement of [125I]-CCK-8 from human CCK2R expressed in human 1321N1 cell membranes after 2 hrs by SPA assay	B	9.54	pIC50	0.29	nM	IC50	J Med Chem (2019) 62: 1407-1419 [PMID:30624060]
ChEMBL	Binding affinity against human Cholecystokinin type B receptor by displacement of [125I]CCK-8	B	9.64	pIC50	0.23	nM	IC50	J. Med. Chem. (1996) 39: 2655-2658 [PMID:8709093]
ChEMBL	Displacement of [125I]CCK-8s from human recombinant CCK-B receptor expressed in CHO cells	B	9.92	pIC50	0.12	nM	IC50	Bioorg. Med. Chem. (2016) 24: 1793-1810 [PMID:26988801]
ChEMBL	Displacement of [125I]CCK-8s from human recombinant CCK2 receptor expressed in CHO cells measured after 60 mins by scintillation counting method	B	9.92	pIC50	0.12	nM	IC50	Bioorg Med Chem (2017) 25: 471-482 [PMID:27876250]
GtoPdb	-	-	10	pIC50	-	-	-	J Biol Chem (1993) 268: 8164-9 [PMID:7681836]; J Biol Chem (1993) 268: 18300-5 [PMID:8349705]
ChEMBL	Antagonist activity at CCK2 receptor expressed in HEK293 cells assessed as accumulation of [3H]inositol phosphates by PI assay	F	7.57	pEC50	27	nM	EC50	J. Med. Chem. (2006) 49: 2868-2875 [PMID:16686530]
ChEMBL	Antagonist activity at CCK2 receptor expressed in HEK293 cells assessed as accumulation of [3H]inositol phosphates by PI assay	F	7.57	pEC50	26.92	nM	EC50	J. Med. Chem. (2006) 49: 2868-2875 [PMID:16686530]
ChEMBL	Agonist activity at human CCK2R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assay	F	9.3	pEC50	0.5	nM	EC50	J Med Chem (2019) 62: 1407-1419 [PMID:30624060]
ChEMBL	Displacement of [125I]CCK-8 from CCK2 receptor in human FGS7 Jurkat cells	B	10.03	pEC50	0.09	nM	EC50	J. Nat. Prod. (2006) 69: 432-435 [PMID:16562853]
ChEMBL	Compound was evaluated for the [Ca2+] mobilization innstably transfected CHO-K1 cell lines expressing human Cholecystokinin type B receptor	B	10.3	pEC50	0.05	nM	EC50	J. Med. Chem. (1995) 38: 3384-3390 [PMID:7650691]
CCK2 receptor/Cholecystokinin B receptor in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2854] [GtoPdb: 77] [UniProtKB: P56481]
ChEMBL	In vitro binding affinity against Cholecystokinin type B receptor in mouse cerebral cortical membranes using [125I]Tyr(SO3H)27]-CCK-8 binding assay	B	8.89	pIC50	1.3	nM	IC50	Bioorg. Med. Chem. Lett. (2001) 11: 705-709 [PMID:11266174]
ChEMBL	Evaluated for inhibition of cholecystokinin type B receptor by displacing [125I]-Bolton hunter CCK-8 radioligand in the mouse cerebral cortex	B	9.52	pIC50	0.3	nM	IC50	J. Med. Chem. (1992) 35: 2573-2581 [PMID:1635058]
ChEMBL	Inhibition of binding of [125I]Bolton-Hunter labeled CCK-8 to cholecystokinin type B receptor in the mouse cerebral cortex	B	9.52	pIC50	0.3	nM	IC50	J. Med. Chem. (1993) 36: 552-565 [PMID:7684452]
ChEMBL	Binding affinity towards Cholecystokinin type B receptor in mouse cortex membrane	B	9.52	pIC50	0.3	nM	IC50	Bioorg. Med. Chem. Lett. (2000) 10: 1245-1248 [PMID:10866391]
ChEMBL	Half-maximal inhibition of specific binding of [125I]bolton hunter CCK-8 to mouse cerebral cortex cholecystokinin type B receptor	B	9.52	pIC50	0.3	nM	IC50	J. Med. Chem. (1991) 34: 404-414 [PMID:1671419]
ChEMBL	Inhibition of [125I]- Bolton-Hunter CCK-26-33 binding to Cholecystokinin type B receptor of mouse cerebral cortex	B	9.52	pIC50	0.3	nM	IC50	Bioorg. Med. Chem. Lett. (1993) 3: 889-894
CCK2 receptor/Cholecystokinin B receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3508] [GtoPdb: 77] [UniProtKB: P30553]
ChEMBL	Inhibition of [3H]- pCCK-8 binding to Cholecystokinin type B receptor of rat cerebral cortex membranes	B	8.55	pKi	2.8	nM	Ki	J. Med. Chem. (1997) 40: 3402-3407 [PMID:9341915]
ChEMBL	Ability to displace 1 nM [3H]pCCK-8 from rat Cholecystokinin type B receptor stably expressing in CHO cells	B	9.15	pKi	0.7	nM	Ki	Bioorg. Med. Chem. Lett. (2004) 14: 369-372 [PMID:14698161]
ChEMBL	Affinity to inhibit [3H]pCCK-8 specific binding on rat brain Cholecystokinin type B receptor expressed in CHO cells	B	9.22	pKi	0.6	nM	Ki	J. Med. Chem. (1997) 40: 647-658 [PMID:9057851]
ChEMBL	Compound was tested for binding affinity against Cholecystokinin type B receptor expressed in CHO cells on the rat brain.	B	9.22	pKi	0.6	nM	Ki	J. Med. Chem. (2000) 43: 3614-3623 [PMID:11020275]
ChEMBL	Binding affinity for Cholecystokinin type B receptor using [125I]-BH-CCK-8 in rat cortex synaptosomes	B	9.39	pKi	0.41	nM	Ki	J. Med. Chem. (1997) 40: 4302-4307 [PMID:9435899]
ChEMBL	Binding affinity towards Cholecystokinin type B receptor in rat cortex synaptosomes using [125I]BH-CCK-8 as radioligand	B	9.39	pKi	0.41	nM	Ki	J. Med. Chem. (2000) 43: 2350-2355 [PMID:10882360]
ChEMBL	Tested for the inhibition of specific [3H]propionyl-CCK-8 binding to rat cerebral cortex membrane(CCK-B)	B	8.22	pIC50	6	nM	IC50	Bioorg. Med. Chem. Lett. (1997) 7: 855-860
ChEMBL	Binding affinity by competitive inhibition of the radioligand [3H]pCCK-8 at Cholecystokinin type B receptor from rat cerebral cortex membrane	B	8.25	pIC50	5.6	nM	IC50	J. Med. Chem. (1999) 42: 4659-4668 [PMID:10579828]
ChEMBL	Inhibition of [3H]pCCK-8 binding to cholecystokinin type B receptor of rat cerebral cortex	B	8.25	pIC50	5.6	nM	IC50	J. Med. Chem. (2001) 44: 4196-4206 [PMID:11708921]
ChEMBL	Inhibition of [3H]-pCCK-8 binding to Cholecystokinin type B receptor of rat cerebral cortex homogenates	B	8.25	pIC50	5.6	nM	IC50	J. Med. Chem. (2004) 47: 5318-5329 [PMID:15456276]
ChEMBL	Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex	B	9	pIC50	1	nM	IC50	J. Med. Chem. (1992) 35: 28-38 [PMID:1732532]
ChEMBL	Effective concentration for the stimulation of Inositol Phosphate accumulation in CHO cells expressing wild-type Cholecystokinin type B receptor	F	9.2	pEC50	0.63	nM	EC50	J. Med. Chem. (1997) 40: 647-658 [PMID:9057851]
ChEMBL	Affinity against Cholecystokinin type B receptor expressed in CHO cells on rat brain.	F	9.2	pEC50	0.63	nM	EC50	J. Med. Chem. (2000) 43: 3614-3623 [PMID:11020275]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]