monomethyl fumarate [Ligand Id: 5786] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL589586 (Bafiertam, Fumaric acid monomethyl ester, Methyl Fumarate, Monomethyl fumarate, NSC-523835) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| HCA2 receptor/Hydroxycarboxylic acid receptor 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3785] [GtoPdb: 312] [UniProtKB: Q8TDS4] | ||||||||
| GtoPdb | - | - | 6.74 | pKi | 180 | nM | Ki | Bioorg Med Chem Lett (2011) 21: 2736-9 [PMID:21167710] |
| ChEMBL | Displacement of [3H]nicotinic acid from human GPR109a receptor expressed in human HEK293T cells by liquid scintillation counting | B | 6.74 | pKi | 180 | nM | Ki | Bioorg Med Chem Lett (2011) 21: 2736-2739 [PMID:21167710] |
| GtoPdb | - | - | 5.03 | pEC50 | 9400 | nM | EC50 | Biochem Biophys Res Commun (2008) 375: 562-5 [PMID:18722346] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
