ChEMBL ligand: CHEMBL607400 (Brivaracetam, Briviact, Briviact (in italy: nubriveo), UCB 34714, UCB-34714)
synaptic vesicle glycoprotein 2A/Synaptic vesicle protein 2a in Rat [ChEMBL: CHEMBL4381] [GtoPdb: 2634] [UniProtKB: Q02563] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
synaptic vesicle glycoprotein 2A/Synaptic vesicle protein 2a in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4381] [GtoPdb: 2634] [UniProtKB: Q02563]
ChEMBL	Displacement of [3H]-2-[4-(3-azidophenyl)-2-oxo-1-pyrrolidinyl]butanamide from SV2A levetiracetam binding site in Sprague-Dawley rat cerebral cortex membranes after 120 mins by liquid scintillation counting method	B	6	pKi	<=1000	nM	Ki	EP-1452524-A1. 2-oxo-1-pyrrolidine derivative and its pharmaceutical uses (2004)
GtoPdb	In vitro inhibitory activity against [3H](2S)-2-[4-(3-azidophenyl)-2-oxopyrrolidin-1-yl]butanamide binding to levetiracetam binding site, in rat brain homogenate.	-	7	pIC50	100	nM	IC50	J Med Chem (2004) 47: 530-49 [PMID:14736235]

ChEMBL data shown on this page come from version 35:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]