AC265347 [Ligand Id: 3947] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1256367
  • CaS receptor/Calcium sensing receptor in Human [ChEMBL: CHEMBL1878] [GtoPdb: 54] [UniProtKB: P41180]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
CaS receptor/Calcium sensing receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1878] [GtoPdb: 54] [UniProtKB: P41180]
ChEMBL Positive allosteric modulation of calcium sensing receptor by cell based assay B 7.6 pEC50 25.12 nM EC50 Bioorg. Med. Chem. Lett. (2010) 20: 5918-5921 [PMID:20727747]
GtoPdb - - 8.1 pEC50 - - - J. Pharmacol. Exp. Ther. (2011) 337: 275-84 [PMID:21239511]

ChEMBL data shown on this page come from version 27:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]