MUT056399 [Ligand Id: 11000] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL2178284
  • Enoyl-[acyl-carrier-protein] reductase [NADPH] in S.aureus [ChEMBL: CHEMBL2176859] [UniProtKB: Q9RMI3]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Enoyl-[acyl-carrier-protein] reductase [NADPH] in S.aureus (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2176859] [UniProtKB: Q9RMI3]
ChEMBL Inhibition of Staphylococcus aureus recombinant FabI using trans-2-octenoyl N-acetylcysteamine thioester as substrate preincubated for 60 mins B 7.92 pIC50 12 nM IC50 J. Med. Chem. (2012) 55: 9914-9928 [PMID:23092194]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]