ChEMBL ligand: CHEMBL226403
MAPK activated protein kinase 2/MAP kinase-activated protein kinase 2 in Human [ChEMBL: CHEMBL2208] [GtoPdb: 2094] [UniProtKB: P49137] This target only has 0 pki data point 0 1 CHEMBL226403_lig_chart_1 MAP kinase-activated protein kinase 2 Human There should be some charts here, you may need to enable JavaScript!
MAPK activated protein kinase 3/MAP kinase-activated protein kinase 3 in Human [ChEMBL: CHEMBL4670] [GtoPdb: 2095] [UniProtKB: Q16644] This target only has 0 pki data point 0 2 CHEMBL226403_lig_chart_2 MAP kinase-activated protein kinase 3 Human There should be some charts here, you may need to enable JavaScript!
MAPK activated protein kinase 5/MAP kinase-activated protein kinase 5 in Human [ChEMBL: CHEMBL3094] [GtoPdb: 2096] [UniProtKB: Q8IW41] This target only has 0 pki data point 0 3 CHEMBL226403_lig_chart_3 MAP kinase-activated protein kinase 5 Human There should be some charts here, you may need to enable JavaScript!
mitogen-activated protein kinase 1/MAP kinase ERK2 in Human [ChEMBL: CHEMBL4040] [GtoPdb: 1495] [UniProtKB: P28482] This target only has 0 pki data point 0 4 CHEMBL226403_lig_chart_4 MAP kinase ERK2 Human There should be some charts here, you may need to enable JavaScript!
MAPK interacting serine/threonine kinase 1/MAP kinase-interacting serine/threonine-protein kinase MNK1 in Human [ChEMBL: CHEMBL4718] [GtoPdb: 2104] [UniProtKB: Q9BUB5] This target only has 0 pki data point 0 5 CHEMBL226403_lig_chart_5 MAP kinase-interacting serine/threonine-protein kinase MNK1 Human There should be some charts here, you may need to enable JavaScript!
mitogen-activated protein kinase 14/MAP kinase p38 alpha in Human [ChEMBL: CHEMBL260] [GtoPdb: 1499] [UniProtKB: Q16539] This target only has 0 pki data point 0 6 CHEMBL226403_lig_chart_6 MAP kinase p38 alpha Human There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
MAPK activated protein kinase 2/MAP kinase-activated protein kinase 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2208] [GtoPdb: 2094] [UniProtKB: P49137]
GtoPdb	-	-	8.07	pIC50	8.5	nM	IC50	J Med Chem (2007) 50: 2647-54 [PMID:17480064]
ChEMBL	Inhibition of MK2	B	8.07	pIC50	8.5	nM	IC50	J. Med. Chem. (2007) 50: 2647-2654 [PMID:17480064]
ChEMBL	Inhibition of human recombinant MK2 expressed in Escherichia coli BL21(DE3) after 60 mins	B	8.07	pIC50	8.5	nM	IC50	J. Med. Chem. (2008) 51: 6225-6229 [PMID:18771253]
ChEMBL	Inhibition of MK2 pretreated for 30 mins before substrate addition measured after 2 hrs by IMAP assay	B	7.31	pEC50	49	nM	EC50	Bioorg. Med. Chem. Lett. (2011) 21: 3818-3822 [PMID:21565500]
MAPK activated protein kinase 3/MAP kinase-activated protein kinase 3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4670] [GtoPdb: 2095] [UniProtKB: Q16644]
ChEMBL	Inhibition of MK3	B	6.68	pIC50	210	nM	IC50	J. Med. Chem. (2007) 50: 2647-2654 [PMID:17480064]
GtoPdb	-	-	6.68	pIC50	210	nM	IC50	J Med Chem (2007) 50: 2647-54 [PMID:17480064]
MAPK activated protein kinase 5/MAP kinase-activated protein kinase 5 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3094] [GtoPdb: 2096] [UniProtKB: Q8IW41]
GtoPdb	-	-	6.09	pIC50	810	nM	IC50	J Med Chem (2007) 50: 2647-54 [PMID:17480064]
ChEMBL	Inhibition of MAPKAPK5 (unknown origin)	B	7	pIC50	100	nM	IC50	J. Med. Chem. (2013) 56: 6991-7002 [PMID:23937569]
ChEMBL	Inhibition of MK5	B	7.09	pIC50	81	nM	IC50	J. Med. Chem. (2007) 50: 2647-2654 [PMID:17480064]
mitogen-activated protein kinase 1/MAP kinase ERK2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4040] [GtoPdb: 1495] [UniProtKB: P28482]
ChEMBL	Inhibition of ERK2	B	5.46	pIC50	3440	nM	IC50	J. Med. Chem. (2007) 50: 2647-2654 [PMID:17480064]
MAPK interacting serine/threonine kinase 1/MAP kinase-interacting serine/threonine-protein kinase MNK1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4718] [GtoPdb: 2104] [UniProtKB: Q9BUB5]
ChEMBL	Inhibition of MNK1	B	5.24	pIC50	5700	nM	IC50	J. Med. Chem. (2007) 50: 2647-2654 [PMID:17480064]
mitogen-activated protein kinase 14/MAP kinase p38 alpha in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL260] [GtoPdb: 1499] [UniProtKB: Q16539]
ChEMBL	Inhibition of p38alpha	B	4	pIC50	>100000	nM	IC50	J. Med. Chem. (2007) 50: 2647-2654 [PMID:17480064]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]