WP814 [Ligand Id: 8762] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL2074989
  • ABCC1/Multidrug resistance-associated protein 1 in Human [ChEMBL: CHEMBL3004] [GtoPdb: 779] [UniProtKB: P33527]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
ABCC1/Multidrug resistance-associated protein 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3004] [GtoPdb: 779] [UniProtKB: P33527]
GtoPdb - - 7.15 pKi 70 nM Ki Biochem. Biophys. Res. Commun. (1998) 247: 859-63 [PMID:9647783]
ChEMBL TP_TRANSPORTER: inhibition of LTC4 uptake in membrane vesicles from SR3A cells F 7.22 pKi 60 nM Ki Biochem. Biophys. Res. Commun. (1998) 247: 859-863 [PMID:9647783]

ChEMBL data shown on this page come from version 26:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]