eribaxaban [Ligand Id: 7408] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL476186 (292, Eribaxaban, PD-0348292, PD 348, PD-348, PD 348,292, PD-348292) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| coagulation factor X/Coagulation factor X in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL244] [GtoPdb: 2359] [UniProtKB: P00742] | ||||||||
| GtoPdb | - | - | 9.24 | pIC50 | 0.57 | nM | IC50 | Bioorg Med Chem (2009) 17: 2501-11 [PMID:19231206] |
| ChEMBL | Inhibition of human Factor-10a | B | 9.24 | pIC50 | 0.57 | nM | IC50 | Bioorg Med Chem (2009) 17: 2501-2511 [PMID:19231206] |
| ChEMBL | Inhibition of factor 10a | B | 9.49 | pIC50 | 0.32 | nM | IC50 | J Med Chem (2010) 53: 6243-6274 [PMID:20503967] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
