ITP [Ligand Id: 1743] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1233686 (Inosine-5'-Triphosphate)
  • P2Y4 receptor in Human [GtoPdb: 325] [UniProtKB: P51582]
  • P2Y4 receptor in Rat [GtoPdb: 325] [UniProtKB: O35811]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
P2Y4 receptor in Human [GtoPdb: 325] [UniProtKB: P51582]
GtoPdb - - 5.1 pEC50 - - - Mol Pharmacol (2000) 57: 926-31 [PMID:10779375]
P2Y4 receptor in Rat [GtoPdb: 325] [UniProtKB: O35811]
GtoPdb - - 5.8 pEC50 - - - Br J Pharmacol (1998) 124: 428-30 [PMID:9647463];
Mol Pharmacol (2000) 57: 926-31 [PMID:10779375]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]