ChEMBL ligand: CHEMBL485832 (5'-Guanidinonaltrindole, 5`-Guanidinonaltrindole, 5'-Guanidinylnaltrindole, C5'-Guanidinyl Naltrindole, Guanidinonaltrindole)
δ receptor/Delta opioid receptor in Human [ChEMBL: CHEMBL236] [GtoPdb: 317] [UniProtKB: P41143] δ receptor/Delta opioid receptor in Mouse [ChEMBL: CHEMBL3222] [GtoPdb: 317] [UniProtKB: P32300] δ receptor/Delta opioid receptor in Rat [ChEMBL: CHEMBL269] [GtoPdb: 317] [UniProtKB: P33533] There should be some charts here, you may need to enable JavaScript!
κ receptor/Kappa opioid receptor in Human [ChEMBL: CHEMBL237] [GtoPdb: 318] [UniProtKB: P41145] κ receptor/Kappa opioid receptor in Rat [ChEMBL: CHEMBL3614] [GtoPdb: 318] [UniProtKB: P34975] Kappa opioid receptor in Guinea pig [ChEMBL: CHEMBL3952] [UniProtKB: P41144] There should be some charts here, you may need to enable JavaScript!
μ receptor/Mu opioid receptor in Human [ChEMBL: CHEMBL233] [GtoPdb: 319] [UniProtKB: P35372] μ receptor/Mu opioid receptor in Rat [ChEMBL: CHEMBL270] [GtoPdb: 319] [UniProtKB: P33535] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
δ receptor/Delta opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL236] [GtoPdb: 317] [UniProtKB: P41143]
ChEMBL	Antagonistic activity against human cloned Opioid receptor delta 1 using DPDPE in [35S]GTP-gamma-S, assay	F	7.81	pKd	15.49	nM	Kd	J Med Chem (2003) 46: 3127-3137 [PMID:12825951]
δ receptor/Delta opioid receptor in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3222] [GtoPdb: 317] [UniProtKB: P32300]
ChEMBL	Displacement of [3H]- diprenorphine from delta receptor expressed in HEK 293 cells	B	7.34	pKi	46.2	nM	Ki	J Med Chem (2001) 44: 857-862 [PMID:11300867]
ChEMBL	Binding affinity towards mouse delta-opioid receptor was determined using [3H]diprenorphine as radioligand	B	7.61	pKi	24.8	nM	Ki	J Med Chem (2001) 44: 2073-2079 [PMID:11405645]
ChEMBL	Displacement of [3H]- diprenorphine from delta-W284E-receptor expressed in HEK 293 cells	B	8.96	pKi	1.1	nM	Ki	J Med Chem (2001) 44: 857-862 [PMID:11300867]
δ receptor/Delta opioid receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL269] [GtoPdb: 317] [UniProtKB: P33533]
ChEMBL	Inhibition of [3H]-DADLE binding to Opioid receptor delta 1 of rat brain tissue	B	7.15	pKi	70	nM	Ki	J Med Chem (2003) 46: 3127-3137 [PMID:12825951]
ChEMBL	Binding affinity on HEK293 cells transiently transfected with plasmids encoding the rat Opioid receptor delta 1	B	7.34	pKi	46.2	nM	Ki	J Med Chem (2000) 43: 2759-2769 [PMID:10893314]
κ receptor/Kappa opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL237] [GtoPdb: 318] [UniProtKB: P41145]
ChEMBL	Antagonistic activity against human cloned kOpioid receptor kappa 1 using U69,593 in [35S]GTP-gamma-S, assay	F	10.4	pKd	0.04	nM	Kd	J Med Chem (2003) 46: 3127-3137 [PMID:12825951]
ChEMBL	Displacement of [125I]-IBNalA from KOR-1 expressed in CHO cells	B	9.72	pKi	0.19	nM	Ki	Bioorg Med Chem Lett (2011) 21: 4001-4004 [PMID:21621410]
ChEMBL	Displacement of [125I]-IBNtxA from KOR-1 expressed in CHO cells	B	9.82	pKi	0.15	nM	Ki	Bioorg Med Chem Lett (2011) 21: 4001-4004 [PMID:21621410]
GtoPdb	-	-	9.9	pKi	-	-	-	Binding and activity of opioid ligands at the cloned human delta, mu and kappa receptors.. The Delta Receptor (2003); Eur J Pharmacol (2000) 396: 49-52 [PMID:10822054]; J Med Chem (2000) 43: 2759-69 [PMID:10893314]
κ receptor/Kappa opioid receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3614] [GtoPdb: 318] [UniProtKB: P34975]
ChEMBL	Mutant factor of the compound against kappa[E297K] with Opioid receptor kappa 1 for binding affinity.	B	7.89	pKi	12.9	nM	Ki	J Med Chem (1998) 41: 4911-4914 [PMID:9836606]
ChEMBL	Effect on binding to kappa(Glu297Ala) opioid receptor, using [3H]diprenorphine in transiently expressed rat HEK293 cells	B	8.41	pKi	3.93	nM	Ki	J Med Chem (2001) 44: 2073-2079 [PMID:11405645]
ChEMBL	Displacement of [3H]diprenorphine from k-E297A-receptor expressed in HEK 293 cells	B	8.41	pKi	3.9	nM	Ki	J Med Chem (2001) 44: 857-862 [PMID:11300867]
ChEMBL	Effect on binding to wild-type opioid receptor kappa 1 using [3H]diprenorphine in transiently expressed rat HEK293 cells	B	9.68	pKi	0.21	nM	Ki	J Med Chem (2001) 44: 2073-2079 [PMID:11405645]
ChEMBL	Binding affinity on HEK293 cells transiently transfected with plasmids encoding the rat Opioid receptor kappa 1	B	9.74	pKi	0.18	nM	Ki	J Med Chem (2000) 43: 2759-2769 [PMID:10893314]
ChEMBL	Displacement of [3H]diprenorphine from opioid receptor kappa 1 expressed in HEK 293 cells	B	9.74	pKi	0.18	nM	Ki	J Med Chem (2001) 44: 857-862 [PMID:11300867]
ChEMBL	Binding affinity towards rat opioid receptor kappa 1 was determined using [3H]diprenorphine radioligand	B	9.85	pKi	0.14	nM	Ki	J Med Chem (2001) 44: 2073-2079 [PMID:11405645]
ChEMBL	Effect on binding affinity of mutational exchange of Glu297 in the Opioid receptor kappa 1 in transiently expressed rat cos-7 cells activity expressed as binding affinity.	B	10.05	pKi	0.09	nM	Ki	J Med Chem (1998) 41: 4911-4914 [PMID:9836606]
ChEMBL	Mutant factor of the compound against mu-[K303E] with Opioid receptor kappa 1 for binding affinity	B	10.22	pKi	0.06	nM	Ki	J Med Chem (1998) 41: 4911-4914 [PMID:9836606]
ChEMBL	Displacement of [3H]diprenorphine from k-Y312A-receptor expressed in HEK 293 cells	B	10.52	pKi	0.03	nM	Ki	J Med Chem (2001) 44: 857-862 [PMID:11300867]
Kappa opioid receptor in Guinea pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3952] [UniProtKB: P41144]
ChEMBL	Inhibition of [3H]U-69593 binding to Opioid receptor kappa 1 of guinea pig brain	B	9.74	pKi	0.18	nM	Ki	J Med Chem (2003) 46: 3127-3137 [PMID:12825951]
μ receptor/Mu opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL233] [GtoPdb: 319] [UniProtKB: P35372]
ChEMBL	Antagonistic activity against human cloned Opioid receptor mu 1 using DPDPE in [35S]GTP-gamma-S, assay	F	8.49	pKd	3.24	nM	Kd	J Med Chem (2003) 46: 3127-3137 [PMID:12825951]
μ receptor/Mu opioid receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL270] [GtoPdb: 319] [UniProtKB: P33535]
ChEMBL	Binding affinity towards rat mu-opioid receptor was determined using [3H]diprenorphine as radioligand	B	7	pKi	99.7	nM	Ki	J Med Chem (2001) 44: 2073-2079 [PMID:11405645]
ChEMBL	Inhibition of [3H]DAMGO binding to Opioid receptor mu 1 of rat brain tissue	B	7.43	pKi	36.9	nM	Ki	J Med Chem (2003) 46: 3127-3137 [PMID:12825951]
ChEMBL	Displacement of [3H]- diprenorphine from mu-receptor expressed in HEK 293 cells	B	7.65	pKi	22.5	nM	Ki	J Med Chem (2001) 44: 857-862 [PMID:11300867]
ChEMBL	Binding affinity on HEK293 cells transiently transfected with plasmids encoding the rat Opioid receptor mu 1	B	7.65	pKi	22.5	nM	Ki	J Med Chem (2000) 43: 2759-2769 [PMID:10893314]
ChEMBL	Effect on binding affinity of mutational exchange of Lys303 in the Opioid receptor mu 1 in transiently expressed rat cos-7 cells activity expressed as binding affinity.	B	8.03	pKi	9.23	nM	Ki	J Med Chem (1998) 41: 4911-4914 [PMID:9836606]
ChEMBL	Displacement of [3H]- diprenorphine from mu-W318A-receptor expressed in HEK 293 cells	B	9.3	pKi	0.5	nM	Ki	J Med Chem (2001) 44: 857-862 [PMID:11300867]
ChEMBL	Displacement of [3H]- diprenorphine from mu-K303E-receptor expressed in HEK 293 cells	B	10.05	pKi	0.09	nM	Ki	J Med Chem (2001) 44: 857-862 [PMID:11300867]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]