CI-966 [Ligand Id: 4612] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL77287 (CI-966)
  • GAT1/GABA transporter 1 in Human [ChEMBL: CHEMBL1903] [GtoPdb: 929] [UniProtKB: P30531]
  • This target only has 0 pki data point
  • 0
1 CHEMBL77287_lig_chart_1 GABA transporter 1 Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
GAT1/GABA transporter 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1903] [GtoPdb: 929] [UniProtKB: P30531]
ChEMBL Inhibitory activity against human GABA transporter-1 (hGAT1) B 6.59 pIC50 260 nM IC50 J. Med. Chem. (1994) 37: 2334-2342 [PMID:8057281]
GtoPdb - - 6.6 pIC50 260 nM IC50 Eur J Pharmacol (1994) 269: 219-24 [PMID:7851497]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]