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ChEMBL ligand: CHEMBL1500 (Dihydromorphine) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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δ receptor in Human [GtoPdb: 317] [UniProtKB: P41143] | ||||||||
GtoPdb | - | - | 6.7 | pKi | - | - | - | NIDA Res Monogr (1998) 178: 440-66 [PMID:9686407] |
δ receptor/Delta opioid receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL269] [GtoPdb: 317] [UniProtKB: P33533] | ||||||||
ChEMBL | Affinity against the Opioid receptor delta 1 | B | 7 | pKd | 100 | nM | Kd | J. Med. Chem. (1986) 29: 531-537 [PMID:3007760] |
κ receptor in Human [GtoPdb: 318] [UniProtKB: P41145] | ||||||||
GtoPdb | - | - | 7.1 | pKi | - | - | - | NIDA Res Monogr (1998) 178: 440-66 [PMID:9686407] |
κ receptor/Kappa opioid receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3614] [GtoPdb: 318] [UniProtKB: P34975] | ||||||||
ChEMBL | Compound was evaluated for Opioid receptor kappa 1 affinity against the receptor site model site 4(kappa) | B | 6.08 | pKd | 830 | nM | Kd | J. Med. Chem. (1986) 29: 531-537 [PMID:3007760] |
μ receptor in Human [GtoPdb: 319] [UniProtKB: P35372] | ||||||||
GtoPdb | - | - | 8.8 | pKi | - | - | - | NIDA Res Monogr (1998) 178: 440-66 [PMID:9686407] |
μ receptor/Mu opioid receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL270] [GtoPdb: 319] [UniProtKB: P33535] | ||||||||
ChEMBL | Opioid receptor mu 2 affinity against the receptor site model site 2(mu2) | B | 8 | pKd | 10 | nM | Kd | J. Med. Chem. (1986) 29: 531-537 [PMID:3007760] |
ChEMBL | Evaluated for Opioid receptor mu 1 affinity against the receptor site model site 1(mu1) | B | 9.7 | pKd | 0.2 | nM | Kd | J. Med. Chem. (1986) 29: 531-537 [PMID:3007760] |
ChEMBL data shown on this page come from version 31:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]