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Compound class: Synthetic organic
Comment: This is the 1S, 2R optical isomer of NCL-1. This isomer is more biologically active than the 1R, 2S isomer .
Histone demethylation by KDM1A is suggested to be associated with some cancers and herpes simplex infection [1,3]. So, KDM1A inhibitors are of interest both as investigational tools and potential disease modifiers.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
|Compound class||Synthetic organic|
|GtoPdb PubChem SID||178103603|
|Search Google for chemical match using the InChIKey||DTPSXFMGMQOVTG-ISJGIBHGSA-N|
|Search Google for chemicals with the same backbone||DTPSXFMGMQOVTG|
|Search UniChem for chemical match using the InChIKey||DTPSXFMGMQOVTG-ISJGIBHGSA-N|
|Search UniChem for chemicals with the same backbone||DTPSXFMGMQOVTG|