HTS01037 [Ligand Id: 6736] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1077990 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| fatty acid binding protein 4/Fatty acid binding protein adipocyte in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2083] [GtoPdb: 2534] [UniProtKB: P15090] | ||||||||
| ChEMBL | Displacement of radiolabeled 1-anilinonaphthalene 8-sulfonic acid from AFABP expressed in Escherichia coli BL21 (DE3) by fluorescence spectrophotometry | B | 6.17 | pKi | 670 | nM | Ki | J Med Chem (2009) 52: 6024-6031 [PMID:19754198] |
| fatty acid binding protein 4 in Mouse [GtoPdb: 2534] [UniProtKB: P04117] | ||||||||
| GtoPdb | - | - | 6.17 | pKi | 670 | nM | Ki | J Med Chem (2009) 52: 6024-31 [PMID:19754198] |
| fatty acid binding protein 5/Fatty acid binding protein epidermal in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3674] [GtoPdb: 2535] [UniProtKB: Q01469] | ||||||||
| ChEMBL | Displacement of radiolabeled 1-anilinonaphthalene 8-sulfonic acid from EFABP expressed in Escherichia coli BL21 (DE3) by fluorescence spectrophotometry | B | 5.47 | pKi | 3400 | nM | Ki | J Med Chem (2009) 52: 6024-6031 [PMID:19754198] |
| fatty acid binding protein 2/Fatty acid binding protein intestinal in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4879] [GtoPdb: 2532] [UniProtKB: P12104] | ||||||||
| ChEMBL | Displacement of radiolabeled 1-anilinonaphthalene 8-sulfonic acid from IFABP expressed in Escherichia coli BL21 (DE3) by fluorescence spectrophotometry | B | 5.18 | pKi | 6570 | nM | Ki | J Med Chem (2009) 52: 6024-6031 [PMID:19754198] |
| fatty acid binding protein 1/Fatty acid-binding protein, liver in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5421] [GtoPdb: 2531] [UniProtKB: P07148] | ||||||||
| ChEMBL | Displacement of radiolabeled 1-anilinonaphthalene 8-sulfonic acid from LFABP expressed in Escherichia coli BL21 (DE3) by fluorescence spectrophotometry | B | 5.09 | pKi | 8170 | nM | Ki | J Med Chem (2009) 52: 6024-6031 [PMID:19754198] |
| fatty acid binding protein 1 in Mouse [GtoPdb: 2531] [UniProtKB: P12710] | ||||||||
| GtoPdb | - | - | 5.09 | pKi | 8170 | nM | Ki | J Med Chem (2009) 52: 6024-31 [PMID:19754198] |
| fatty acid binding protein 3/Fatty acid binding protein muscle in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3344] [GtoPdb: 2533] [UniProtKB: P05413] | ||||||||
| ChEMBL | Displacement of radiolabeled 1-anilinonaphthalene 8-sulfonic acid from HFABP expressed in Escherichia coli BL21 (DE3) by fluorescence spectrophotometry | B | 5.04 | pKi | 9070 | nM | Ki | J Med Chem (2009) 52: 6024-6031 [PMID:19754198] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
