fatty acid binding protein 3 | Fatty acid-binding proteins | IUPHAR/BPS Guide to PHARMACOLOGY

Top ▲

fatty acid binding protein 3

Target not currently curated in GtoImmuPdb

Target id: 2533

Nomenclature: fatty acid binding protein 3

Family: Fatty acid-binding proteins

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 133 1p33-p32 FABP3 fatty acid binding protein 3
Mouse - 133 4 D2.2 Fabp3 fatty acid binding protein 3, muscle and heart
Rat - 133 5q36 Fabp3 fatty acid binding protein 3
Previous and Unofficial Names
FABP11 | Fabph1 | Fabph4 | fatty acid binding protein 11 | H-FABP | MDGI | mammary-derived growth inhibitor
Database Links
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
RefSeq Nucleotide
RefSeq Protein
Rank order of potency (Human)
stearic acid, oleic acid, palmitic acid > linoleic acid, α-linolenic acid, arachidonic acid  [1]

Download all structure-activity data for this target as a CSV file

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
compound 13 [PMID: 17502136] Hs Inhibition 8.4 pKi 2
pKi 8.4 (Ki 4x10-9 M) [2]


Show »

1. Richieri GV, Ogata RT, Kleinfeld AM. (1994) Equilibrium constants for the binding of fatty acids with fatty acid-binding proteins from adipocyte, intestine, heart, and liver measured with the fluorescent probe ADIFAB. J. Biol. Chem., 269 (39): 23918-30. [PMID:7929039]

2. Sulsky R, Magnin DR, Huang Y, Simpkins L, Taunk P, Patel M, Zhu Y, Stouch TR, Bassolino-Klimas D, Parker R et al.. (2007) Potent and selective biphenyl azole inhibitors of adipocyte fatty acid binding protein (aFABP). Bioorg. Med. Chem. Lett., 17 (12): 3511-5. [PMID:17502136]

How to cite this page

Fatty acid-binding proteins: fatty acid binding protein 3. Last modified on 12/07/2018. Accessed on 24/08/2019. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2533.