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fatty acid binding protein 3

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Target not currently curated in GtoImmuPdb

Target id: 2533

Nomenclature: fatty acid binding protein 3

Family: Fatty acid-binding proteins

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 133 1p35.2 FABP3 fatty acid binding protein 3
Mouse - 133 4 63.43 cM Fabp3 fatty acid binding protein 3, muscle and heart
Rat - 133 5q36 Fabp3 fatty acid binding protein 3
Previous and Unofficial Names Click here for help
MDGI | FABP11 | Fabph1 | Fabph4 | fatty acid binding protein 11 | H-FABP | mammary-derived growth inhibitor
Database Links Click here for help
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
RefSeq Nucleotide
RefSeq Protein
Rank order of potency (Human)
stearic acid, oleic acid, palmitic acid > linoleic acid, α-linolenic acid, arachidonic acid  [1]

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Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
compound 13 [PMID: 17502136] Small molecule or natural product Click here for species-specific activity table Hs Inhibition 8.4 pKi 2
pKi 8.4 (Ki 4x10-9 M) [2]


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1. Richieri GV, Ogata RT, Kleinfeld AM. (1994) Equilibrium constants for the binding of fatty acids with fatty acid-binding proteins from adipocyte, intestine, heart, and liver measured with the fluorescent probe ADIFAB. J Biol Chem, 269 (39): 23918-30. [PMID:7929039]

2. Sulsky R, Magnin DR, Huang Y, Simpkins L, Taunk P, Patel M, Zhu Y, Stouch TR, Bassolino-Klimas D, Parker R et al.. (2007) Potent and selective biphenyl azole inhibitors of adipocyte fatty acid binding protein (aFABP). Bioorg Med Chem Lett, 17 (12): 3511-5. [PMID:17502136]

How to cite this page

Fatty acid-binding proteins: fatty acid binding protein 3. Last modified on 12/07/2018. Accessed on 20/04/2024. IUPHAR/BPS Guide to PHARMACOLOGY,