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ChEMBL ligand: CHEMBL49 (BCI-024, Buspar, Buspirone, Gen-buspirone) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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Alpha-1a adrenergic receptor in Bovine (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4892] [UniProtKB: P18130] | ||||||||
ChEMBL | Binding affinity against alpha-1 adrenergic receptor in calf frontal cortex | B | 4.8 | pIC50 | 16000 | nM | IC50 | J Med Chem (1994) 37: 1779-1793 [PMID:7912735] |
α1A-adrenoceptor/Alpha-1a adrenergic receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL319] [GtoPdb: 22] [UniProtKB: P43140] | ||||||||
ChEMBL | DRUGMATRIX: Alpha-1A adrenergic receptor radioligand binding (ligand: prazosin) | B | 5.85 | pKi | 1410 | nM | Ki | DrugMatrix in vitro pharmacology data |
ChEMBL | DRUGMATRIX: Alpha-1A adrenergic receptor radioligand binding (ligand: prazosin) | B | 5.46 | pIC50 | 3482 | nM | IC50 | DrugMatrix in vitro pharmacology data |
α1D-adrenoceptor/Alpha-1d adrenergic receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL223] [GtoPdb: 24] [UniProtKB: P25100] | ||||||||
ChEMBL | DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin) | B | 6.28 | pKi | 529 | nM | Ki | DrugMatrix in vitro pharmacology data |
ChEMBL | DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin) | B | 5.97 | pIC50 | 1077 | nM | IC50 | DrugMatrix in vitro pharmacology data |
Alpha-2a adrenergic receptor in Bovine (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4744] [UniProtKB: Q28838] | ||||||||
ChEMBL | Binding affinity against alpha-2 adrenergic receptor in calf frontal cortex | B | 5 | pIC50 | 10000 | nM | IC50 | J Med Chem (1994) 37: 1779-1793 [PMID:7912735] |
Dopamine D1 receptor in Bovine (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2967] [UniProtKB: Q95136] | ||||||||
ChEMBL | Inhibition of [3H]SCH-23390 binding to Dopamine receptor D1 of bovine striatum | B | 5.21 | pKi | 6100 | nM | Ki | J Med Chem (1997) 40: 952-960 [PMID:9083484] |
ChEMBL | Binding affinity towards dopamine receptor D1 in calf striatum | B | 4.57 | pIC50 | 27000 | nM | IC50 | J Med Chem (1994) 37: 1779-1793 [PMID:7912735] |
D1 receptor/Dopamine D1 receptor in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3071] [GtoPdb: 214] [UniProtKB: Q61616] | ||||||||
ChEMBL | Binding affinity against Dopamine receptor D1 | B | 6 | pKi | >1000 | nM | Ki | J Med Chem (1997) 40: 952-960 [PMID:9083484] |
D2 receptor/Dopamine D2 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL217] [GtoPdb: 215] [UniProtKB: P14416] | ||||||||
ChEMBL | Binding affinity against Dopamine receptor D2 | B | 6 | pKi | 1000 | nM | Ki | J Med Chem (1997) 40: 952-960 [PMID:9083484] |
ChEMBL | Displacement of [3H]methylspiperone from human D2 receptor expressed in HEK cells | B | 6.32 | pKi | 484 | nM | Ki | J Med Chem (2018) 61: 2166-2210 [PMID:28850227] |
ChEMBL | Displacement of [3H]methylspiperone from human D2 receptor expressed in HEK-GIRK-M4 cell membrane by radioligand binding assay | B | 6.32 | pKi | 484 | nM | Ki | Bioorg Med Chem Lett (2019) 29: 126667-126667 [PMID:31547945] |
ChEMBL | DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone) | B | 6.97 | pKi | 108 | nM | Ki | DrugMatrix in vitro pharmacology data |
ChEMBL | Binding affinity for DA2 receptor | B | 7.05 | pKi | 90 | nM | Ki | J Med Chem (1993) 36: 3526-3532 [PMID:7902439] |
ChEMBL | Binding affinity to D2 receptor by radioligand binding assay | B | 7.89 | pKi | 13 | nM | Ki | J Med Chem (2006) 49: 3116-3135 [PMID:16722631] |
ChEMBL | Displacement of [3H]U-86170 from human D2-dopamine receptor expressed in CHO K1 cells | B | 7.89 | pKi | 13 | nM | Ki | J Med Chem (1993) 36: 2066-2074 [PMID:8101876] |
ChEMBL | DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone) | B | 6.49 | pIC50 | 323 | nM | IC50 | DrugMatrix in vitro pharmacology data |
Dopamine D2 receptor in Bovine (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3998] [UniProtKB: P20288] | ||||||||
ChEMBL | Inhibition of [3H]raclopride binding to Dopamine receptor D2 of bovine striatum | B | 7.36 | pKi | 44 | nM | Ki | J Med Chem (1997) 40: 952-960 [PMID:9083484] |
ChEMBL | Displacement of [3H]SDZ-205-501 from Dopamine receptor D2 in calf caudate nucleus. | B | 5.4 | pIC50 | 4000 | nM | IC50 | J Med Chem (1996) 39: 4285-4298 [PMID:8863806] |
ChEMBL | Binding affinity against D2 receptor in calf caudate nucleus | B | 5.4 | pIC50 | 4000 | nM | IC50 | J Med Chem (1994) 37: 1779-1793 [PMID:7912735] |
D2 receptor/Dopamine D2 receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL339] [GtoPdb: 215] [UniProtKB: P61169] | ||||||||
ChEMBL | Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand. | B | 6.07 | pKi | 852 | nM | Ki | J Med Chem (1996) 39: 4439-4450 [PMID:8893838] |
ChEMBL | Compound was evaluated for binding affinity against Dopamine receptor D2 using [3H]raclopride as a radioligand | B | 6.07 | pKi | 852 | nM | Ki | Bioorg Med Chem Lett (1996) 6: 689-694 |
ChEMBL | Binding affinity was determined against Dopamine receptor D2 using [3H]spiperone | B | 6.44 | pKi | 367 | nM | Ki | J Med Chem (1995) 38: 4198-4210 [PMID:7473547] |
ChEMBL | Binding affinity towards dopamine receptor D2 by displacing [3H]spiperone radioligand in rat striatum | B | 6.44 | pKi | 367 | nM | Ki | J Med Chem (1992) 35: 552-558 [PMID:1346653] |
ChEMBL | In vitro inhibition of [3H]spiperone binding to Dopamine receptor D2 from rat brain limbic tissue | B | 6.92 | pKi | 119 | nM | Ki | J Med Chem (1988) 31: 1382-1392 [PMID:2898533] |
ChEMBL | In vitro ability to inhibit [3H]spiperone binding to dopamine receptor D2 of rat limbic structures | B | 6.92 | pKi | 119 | nM | Ki | J Med Chem (1989) 32: 1024-1033 [PMID:2565399] |
ChEMBL | Inhibitory activity against rat limbic tissue Dopamine receptor D2 | B | 6.92 | pKi | 119 | nM | Ki | J Med Chem (1999) 42: 5077-5094 [PMID:10602693] |
ChEMBL | In vitro ability to inhibit binding of radioligand [3H]spiroperidol to dopamine D2 receptor in rat striatal membrane | B | 7.38 | pKi | 41.69 | nM | Ki | J Med Chem (1994) 37: 99-104 [PMID:8289207] |
ChEMBL | Binding affinity against Dopamine receptor D2 in rat striatal membrane using [3H]spiroperidol as radioligand | B | 6.55 | pIC50 | 280 | nM | IC50 | J Med Chem (1996) 39: 3195-3202 [PMID:8759642] |
ChEMBL | Binding affinity towards rat Dopamine receptor D2 was evaluated using [3H]- spiroperidol as radioligand | B | 6.55 | pIC50 | 280 | nM | IC50 | J Med Chem (1996) 39: 4928-4934 [PMID:8960552] |
ChEMBL | In vitro binding affinity towards the dopamine receptor D2 at 10 e-6 M | B | 6.58 | pIC50 | 265 | nM | IC50 | J Med Chem (1993) 36: 1509-1510 [PMID:8496920] |
ChEMBL | In vitro binding affinity measured on dopamine receptor D2 using [3H]spiroperidol as radioligand. | B | 6.65 | pIC50 | 226 | nM | IC50 | J Med Chem (1995) 38: 942-949 [PMID:7699710] |
ChEMBL | Inhibition of binding of radioligand [3H]spiroperidol to dopamine D2 receptor in rat striatal membranes | B | 6.65 | pIC50 | 222 | nM | IC50 | J Med Chem (1994) 37: 99-104 [PMID:8289207] |
ChEMBL | Binding affinity to Dopamine receptor D2 in of rat striatum membrane with [3H]- raclopride as radioligand | B | 7.26 | pIC50 | 55 | nM | IC50 | Bioorg Med Chem Lett (2001) 11: 595-598 [PMID:11229779] |
ChEMBL | Inhibitory concentration against Dopamine receptor D2 in rat striatum membrane using [3H]raclopride as radioligand | B | 7.26 | pIC50 | 55 | nM | IC50 | Bioorg Med Chem Lett (2005) 15: 2990-2993 [PMID:15914001] |
D3 receptor/Dopamine D3 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL234] [GtoPdb: 216] [UniProtKB: P35462] | ||||||||
ChEMBL | Inhibition of [3H]spiperone binding to Dopamine receptor D3 in bovine cortex | B | 6.18 | pKi | 660 | nM | Ki | J Med Chem (1997) 40: 952-960 [PMID:9083484] |
ChEMBL | DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone) | B | 7.82 | pKi | 15 | nM | Ki | DrugMatrix in vitro pharmacology data |
ChEMBL | DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone) | B | 7.36 | pIC50 | 44 | nM | IC50 | DrugMatrix in vitro pharmacology data |
Kv11.1/HERG in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL240] [GtoPdb: 572] [UniProtKB: Q12809] | ||||||||
ChEMBL | Inhibition of human ERG | B | 5.4 | pIC50 | 3981.07 | nM | IC50 | Eur J Med Chem (2011) 46: 618-630 [PMID:21185626] |
Multidrug and toxin extrusion/Multidrug and toxin extrusion protein 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1743126] [GtoPdb: 1216] [UniProtKB: Q96FL8] | ||||||||
ChEMBL | Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay | B | 5.77 | pIC50 | 1700 | nM | IC50 | J Med Chem (2013) 56: 781-795 [PMID:23241029] |
MATE2/Multidrug and toxin extrusion protein 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1743127] [GtoPdb: 1217] [UniProtKB: Q86VL8] | ||||||||
ChEMBL | Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay | B | 4.34 | pIC50 | 46000 | nM | IC50 | J Med Chem (2013) 56: 781-795 [PMID:23241029] |
5-HT1A receptor/Serotonin 1a (5-HT1a) receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL214] [GtoPdb: 1] [UniProtKB: P08908] | ||||||||
ChEMBL | Binding affinity to 5HT1A receptor | B | 8 | pKd | 10 | nM | Kd | J Med Chem (2009) 52: 6107-6125 [PMID:19754201] |
ChEMBL | Displacement of [3H]-5-carboxamidotryptamine from human 5-HT1A receptor expressed in HEK293T cell membranes incubated for 90 mins by scintillation counting method | B | 7.3 | pKi | 50 | nM | Ki | Bioorg Med Chem (2020) 28: 115262-115262 [PMID:31882369] |
ChEMBL | Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells after 1 hr by microbeta plate reader analysis | B | 7.46 | pKi | 34.3 | nM | Ki | Eur J Med Chem (2020) 185: 111857-111857 [PMID:31734022] |
ChEMBL | Displacement of [3H]-8-OH-DPAT from 5HT1A receptor (unknown origin) | B | 7.46 | pKi | 34.3 | nM | Ki | ACS Med Chem Lett (2017) 8: 390-394 [PMID:28435524] |
ChEMBL | Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells incubated for 1 hr by liquid scintillation counter method | B | 7.49 | pKi | 32.36 | nM | Ki | Eur J Med Chem (2019) 179: 1-15 [PMID:31229883] |
ChEMBL | Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells incubated for 1 hr by liquid scintillation counter method | B | 7.49 | pKi | 32.2 | nM | Ki | Eur J Med Chem (2019) 179: 1-15 [PMID:31229883] |
ChEMBL | Displacement of [3H]-8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HEK293 cells after 1 hr by microbeta scintillation counting method | B | 7.49 | pKi | 32.2 | nM | Ki | Eur J Med Chem (2019) 170: 261-275 [PMID:30904783] |
ChEMBL | Binding affinity to 5HT1A receptor | B | 7.62 | pKi | 24 | nM | Ki | J Med Chem (2010) 53: 1319-1328 [PMID:20041669] |
ChEMBL | Displacement of [3H]-8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HEK293 cell membrane after 1 hr by Microbeta scintillation counting analysis | B | 7.66 | pKi | 22 | nM | Ki | Eur J Med Chem (2014) 78: 324-339 [PMID:24691057] |
ChEMBL | Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in CHO-K1 cell membranes incubated for 60 mins by microbeta scintillation counting analysis | B | 7.68 | pKi | 21 | nM | Ki | Eur J Med Chem (2019) 183: 111736-111736 [PMID:31586817] |
ChEMBL | Displacement of [3H]5-carboxamidotryptamine to human 5HT1A expressed in HEK293 cells by filter binding assay | B | 7.68 | pKi | 21 | nM | Ki | J Med Chem (2011) 54: 3206-3221 [PMID:21486038] |
ChEMBL | Displacement of [3H]-8-OH-DPAT from human 5-HT1A expressed in human HEK293 cells assessed as inhibitory constant incubated for 1 hr by radioligand binding assay | B | 7.7 | pKi | 20 | nM | Ki | Eur J Med Chem (2019) 178: 740-751 [PMID:31229876] |
ChEMBL | Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells | B | 7.7 | pKi | 20 | nM | Ki | J Med Chem (2006) 49: 3116-3135 [PMID:16722631] |
ChEMBL | Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cells by liquid scintillation counting | B | 7.7 | pKi | 20 | nM | Ki | J Med Chem (2010) 53: 1319-1328 [PMID:20041669] |
ChEMBL | Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells | B | 7.7 | pKi | 20 | nM | Ki | Eur J Med Chem (2016) 112: 258-269 [PMID:26900658] |
ChEMBL | Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method | B | 7.7 | pKi | 20 | nM | Ki | Eur J Med Chem (2020) 201: 112437-112437 [PMID:32673902] |
ChEMBL | Displacement of [3H]-8-OH-DPAT from human 5HT1AR expressed in HEK293 cell membranes after 1 hr by Microbeta scintillation counting method | B | 7.7 | pKi | 20 | nM | Ki | Eur J Med Chem (2018) 147: 102-114 [PMID:29425815] |
ChEMBL | Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cell membranes after 1 hr by microbeta counting method | B | 7.7 | pKi | 20 | nM | Ki | Medchemcomm (2018) 9: 1033-1044 [PMID:30108992] |
ChEMBL | Affinity for 5HT1A receptor | B | 7.77 | pKi | 17 | nM | Ki | Bioorg Med Chem Lett (2006) 16: 3406-3410 [PMID:16677812] |
ChEMBL | Displacement of [3H]8-OH-DPAT from human 5HT1A receptor | B | 7.82 | pKi | 15 | nM | Ki | Bioorg Med Chem Lett (2009) 19: 1159-1163 [PMID:19147349] |
ChEMBL | Binding affinity against human 5-hydroxytryptamine 1A receptor | B | 7.82 | pKi | 15 | nM | Ki | J Med Chem (1997) 40: 952-960 [PMID:9083484] |
ChEMBL | Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells after 1 hr | B | 7.92 | pKi | 12 | nM | Ki | Bioorg Med Chem Lett (2013) 23: 4419-4423 [PMID:23787101] |
GtoPdb | - | - | 8 | pKi | - | - | - |
Biochem J (1992) 285 ( Pt 3): 933-8 [PMID:1386736]; Eur J Pharmacol (1998) 355: 245-56 [PMID:9760039]; Naunyn Schmiedebergs Arch Pharmacol (1998) 357: 205-17 [PMID:9550290] |
ChEMBL | Agonist activity at 5HT1A receptor (unknown origin) | F | 8.05 | pKi | 8.9 | nM | Ki | Eur J Med Chem (2018) 145: 74-85 [PMID:29324345] |
ChEMBL | Binding affinity of compound towards 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT (0.5 nM) ligand in hippocampus + frontal bovine was determined | B | 8.07 | pKi | 8.6 | nM | Ki | J Med Chem (1997) 40: 952-960 [PMID:9083484] |
ChEMBL | Ability to displace [3H]-DPAT from 5-hydroxytryptamine 1A receptor in homogenates of bovine hippocampus. | B | 8.18 | pKi | 6.6 | nM | Ki | J Med Chem (1992) 35: 1076-1092 [PMID:1348089] |
ChEMBL | Displacement of [3H]-8-OH-DAPT from human 5-HT1A receptor expressed in CHO-K1 cells membrane by scintillation counter analysis | B | 8.3 | pKi | 5.01 | nM | Ki | Eur J Med Chem (2022) 233: 114218-114218 [PMID:35248836] |
ChEMBL | Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor stably expressed in CHO-K1 cell membranes measured after 60 mins by Microbeta2 scintillation counting method | B | 8.3 | pKi | 5.01 | nM | Ki | J Med Chem (2020) 63: 10946-10971 [PMID:32883072] |
ChEMBL | Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor stably expressed in CHO-K1 cell membranes measured after 60 mins by microbeta2 scintillation counting method | B | 8.3 | pKi | 5.01 | nM | Ki | J Med Chem (2019) 62: 2750-2771 [PMID:30721053] |
ChEMBL | Binding affinity to 5-HT1A (unknown origin) | B | 8.32 | pKi | 4.78 | nM | Ki | J Med Chem (2018) 61: 2166-2210 [PMID:28850227] |
ChEMBL | Binding affinity to 5HT1A receptor (unknown origin) | B | 8.4 | pKi | 4 | nM | Ki | Bioorg Med Chem Lett (2019) 29: 126667-126667 [PMID:31547945] |
ChEMBL | Displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor of bovine hippocampus. | B | 8.51 | pKi | 3.1 | nM | Ki | J Med Chem (1993) 36: 2066-2074 [PMID:8101876] |
ChEMBL | In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in human CYP3A4 assay | B | 7.6 | pIC50 | 25 | nM | IC50 | Bioorg Med Chem Lett (2004) 14: 1709-1712 [PMID:15026055] |
ChEMBL | Biased agonist activity at Gal4-VP16 transcription factor linked human 5-HT1A receptor expressed in human U2OS cells assessed as stimulation of beta-arrestin recruitment measured after 5 hrs by Tango assay | B | 6.73 | pEC50 | 186.21 | nM | EC50 | J Med Chem (2019) 62: 2750-2771 [PMID:30721053] |
ChEMBL | Biased agonist activity at Gal4-VP16 transcription factor linked human 5-HT1A receptor expressed in human U2OS cells assessed as induction of beta-arrestin2 recruitment measured after 5 hrs by Tango assay | B | 6.73 | pEC50 | 186.21 | nM | EC50 | J Med Chem (2020) 63: 10946-10971 [PMID:32883072] |
ChEMBL | Activity against 5HT1A receptor by Gi-[35S]GTP-gamma-S binding assay | F | 7.1 | pEC50 | 80 | nM | EC50 | J Med Chem (2006) 49: 3116-3135 [PMID:16722631] |
ChEMBL | Biased agonist activity at human recombinant 5-HT1A receptor stably expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation after 40 mins by LANCE Ultra cAMP kit-based TR-FRET assay | F | 7.14 | pEC50 | 72.44 | nM | EC50 | J Med Chem (2019) 62: 2750-2771 [PMID:30721053] |
ChEMBL | Biased agonist activity at human 5-HT1A receptor stably expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation after 40 mins by LANCE Ultra cAMP kit-based TR-FRET assay | F | 7.14 | pEC50 | 72.44 | nM | EC50 | J Med Chem (2020) 63: 10946-10971 [PMID:32883072] |
ChEMBL | Agonist activity at human 5HT1A receptor expressed in CHO cells by FLIPR | F | 7.39 | pEC50 | 41 | nM | EC50 | Bioorg Med Chem Lett (2009) 19: 1159-1163 [PMID:19147349] |
ChEMBL | Biased agonist activity at human 5-HT1A receptor stably expressed in CHO-K1 cells co-expressing Galpha16/GPCR assessed as increase in calcium mobilization measured for 30 secs in presence of coelenterazine by aequorin-reporter gene based luminescence assay | F | 7.42 | pEC50 | 38.02 | nM | EC50 | J Med Chem (2020) 63: 10946-10971 [PMID:32883072] |
ChEMBL | Biased agonist activity at human recombinant 5-HT1A receptor stably expressed in CHO-K1 cells assessed as increase in ERK1/2 phosphorylation levels incubated for 15 mins by Alphalisa assay | B | 7.82 | pEC50 | 15.14 | nM | EC50 | J Med Chem (2019) 62: 2750-2771 [PMID:30721053] |
ChEMBL | Biased agonist activity at human 5-HT1A receptor stably expressed in CHO-K1 cells assessed as increase in ERK1/2 phosphorylation after 15 mins by Alphalisa assay | B | 7.82 | pEC50 | 15.14 | nM | EC50 | J Med Chem (2020) 63: 10946-10971 [PMID:32883072] |
5-HT1A receptor/Serotonin 1a (5-HT1a) receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL273] [GtoPdb: 1] [UniProtKB: P19327] | ||||||||
ChEMBL | Binding affinity for 5-hydroxytryptamine 1A receptor with [3H]5-HT | B | 7.34 | pKi |