IMCgp100   Click here for help

GtoPdb Ligand ID: 7378

Immunopharmacology Ligand
Compound class: Antibody
Comment: IMCgp100 is an immunotherapeutic antibody/peptide fusion, comprising a soluble T cell receptor (TCR) specific for the HLA-A2 restricted melanoma-associated antigen gp100, fused to an anti-CD3 single chain antibody fragment (scFv) [1,3]. This belongs to a novel class of immunotherapeutics termed ImmTACs (Immune Mobilising mTCR against Cancer) which are designed to override immune tolerance to cancer and mobilise T cells to kill cancer cells.
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Compound class Antibody
Database Links Click here for help
GtoPdb PubChem SID 178103950
PubChem SID 178103950