SU-14813 [Ligand Id: 5712] activity data from GtoPdb

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

  • platelet derived growth factor receptor beta in Human [GtoPdb: 1804] [UniProtKB: P09619]
There should be some charts here, you may need to enable JavaScript!
  • KIT proto-oncogene, receptor tyrosine kinase in Human [GtoPdb: 1805] [UniProtKB: P10721]
There should be some charts here, you may need to enable JavaScript!
  • fibroblast growth factor receptor 1 in Human [GtoPdb: 1808] [UniProtKB: P11362]
There should be some charts here, you may need to enable JavaScript!
  • fms related receptor tyrosine kinase 1 in Human [GtoPdb: 1812] [UniProtKB: P17948]
There should be some charts here, you may need to enable JavaScript!
  • kinase insert domain receptor in Human [GtoPdb: 1813] [UniProtKB: P35968]
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
platelet derived growth factor receptor beta in Human [GtoPdb: 1804] [UniProtKB: P09619]
GtoPdb - - 8.4 pIC50 4 nM IC50 Mol. Cancer Ther. (2006) 5: 1774-82 [PMID:16891463]
KIT proto-oncogene, receptor tyrosine kinase in Human [GtoPdb: 1805] [UniProtKB: P10721]
GtoPdb - - 7.82 pIC50 15 nM IC50 Mol. Cancer Ther. (2006) 5: 1774-82 [PMID:16891463]
fibroblast growth factor receptor 1 in Human [GtoPdb: 1808] [UniProtKB: P11362]
GtoPdb - - 5.46 pIC50 3500 nM IC50 Mol. Cancer Ther. (2006) 5: 1774-82 [PMID:16891463]
fms related receptor tyrosine kinase 1 in Human [GtoPdb: 1812] [UniProtKB: P17948]
GtoPdb - - 8.7 pIC50 2 nM IC50 Mol. Cancer Ther. (2006) 5: 1774-82 [PMID:16891463]
kinase insert domain receptor in Human [GtoPdb: 1813] [UniProtKB: P35968]
GtoPdb - - 8.64 pKd 2.3 nM Kd Nat. Biotechnol. (2011) 29: 1046-51 [PMID:22037378]
GtoPdb - - 7.3 pIC50 50 nM IC50 Mol. Cancer Ther. (2006) 5: 1774-82 [PMID:16891463]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.