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ChEMBL ligand: CHEMBL196 (INS-300, Cecon, Redoxon, Vitamin C, Cenolate, Redoxon chew-c, FEMA NO. 2109, Top c, Bassett's, Haliborange, Redoxon slow release, Cetane, Ascur, Vital life, Ascorbic Acid, Ascor, E-300, Cevex, Ascorbic acid (vit c), Cevitamic acid, NSC-218455, Cevalin, Cetane-caps tc, Vitamin c, NSC-33832, Ascorbic acid, E300, Ascorbicap, INS NO.300, Redoxon c, Cebione) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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α2B-adrenoceptor/Alpha-2b adrenergic receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1942] [GtoPdb: 26] [UniProtKB: P18089] | ||||||||
ChEMBL | Agonist activity at human adrenergic alpha2B receptor expressed in HEK293 cells coexpressing Gqi5 protein by FLIPR assay | F | 9.3 | pEC50 | 0.5 | nM | EC50 | Bioorg. Med. Chem. (2009) 17: 2497-2500 [PMID:19243956] |
amylase alpha 2A/Pancreatic alpha-amylase in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2699] [GtoPdb: 2596] [UniProtKB: P00689] | ||||||||
ChEMBL | Inhibitory constant against Alpha-amylase | B | 4.36 | pKi | 43400 | nM | Ki | Bioorg. Med. Chem. Lett. (2000) 10: 1575-1576 [PMID:10915054] |
ChEMBL | The compound was tested for inhibition of malt Alpha-amylase by Megazyme assay | B | 4.58 | pIC50 | 26500 | nM | IC50 | Bioorg. Med. Chem. Lett. (2000) 10: 1575-1576 [PMID:10915054] |
tyrosinase/Tyrosinase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1973] [GtoPdb: 2643] [UniProtKB: P14679] | ||||||||
ChEMBL | Inhibition of tyrosinase (unknown origin) | B | 4.49 | pIC50 | 32500 | nM | IC50 | Bioorg. Med. Chem. Lett. (2015) 25: 1476-1478 [PMID:25726329] |
ChEMBL data shown on this page come from version 28:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]