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amylase alpha 2A

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Target not currently curated in GtoImmuPdb

Target id: 2596

Nomenclature: amylase alpha 2A

Family: 3.2.1.- Glycosidases

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 511 1p21.1 AMY2A amylase alpha 2A
Mouse - 508 3 49.35 cM Amy2a5 amylase 2a5
Rat - 508 2q41 Amy2a3 amylase 2a3
Previous and Unofficial Names Click here for help
amylase alpha 2A (pancreatic) | amylase, alpha 2A (pancreatic) | pancreatic alpha-amylase
Database Links Click here for help
BRENDA
ChEMBL Target
DrugBank Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
Pharos
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction Click here for help
EC Number: 3.2.1.1

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Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
acarbose Small molecule or natural product Approved drug Ligand has a PDB structure Pig Inhibition 4.4 pIC50 1
pIC50 4.4 (IC50 3.55x10-5 M) [1]

References

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1. Patil VS, Nandre KP, Ghosh S, Rao VJ, Chopade BA, Bhosale SV, Bhosale SV. (2012) Synthesis and glycosidase inhibitory activity of novel (2-phenyl-4H-benzopyrimedo[2,1-b]-thiazol-4-yliden)acetonitrile derivatives. Bioorg Med Chem Lett, 22 (23): 7011-4. [PMID:23102653]

How to cite this page

3.2.1.- Glycosidases: amylase alpha 2A. Last modified on 12/09/2019. Accessed on 15/05/2021. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2596.