amylase alpha 2A | 3.2.1.- Glycosidases | IUPHAR/BPS Guide to PHARMACOLOGY

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amylase alpha 2A

Target not currently curated in GtoImmuPdb

Target id: 2596

Nomenclature: amylase alpha 2A

Family: 3.2.1.- Glycosidases

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 511 1p21.1 AMY2A amylase alpha 2A
Mouse - 508 3 F3 Amy2a5 amylase 2a5
Rat - 508 2q41 Amy2a3 amylase 2a3
Previous and Unofficial Names
amylase alpha 2A (pancreatic) | amylase, alpha 2A (pancreatic) | pancreatic alpha-amylase
Database Links
BRENDA
ChEMBL Target
DrugBank Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
Pharos
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction
EC Number: 3.2.1.1

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
acarbose Pig Inhibition 4.4 pIC50 1
pIC50 4.4 (IC50 3.55x10-5 M) [1]

References

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1. Patil VS, Nandre KP, Ghosh S, Rao VJ, Chopade BA, Bhosale SV, Bhosale SV. (2012) Synthesis and glycosidase inhibitory activity of novel (2-phenyl-4H-benzopyrimedo[2,1-b]-thiazol-4-yliden)acetonitrile derivatives. Bioorg. Med. Chem. Lett., 22 (23): 7011-4. [PMID:23102653]

How to cite this page

3.2.1.- Glycosidases: amylase alpha 2A. Last modified on 12/09/2019. Accessed on 26/05/2020. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2596.