nadolol   Click here for help

GtoPdb Ligand ID: 554

Synonyms: Corgard® | corzide | SQ-11725
Approved drug
nadolol is an approved drug (FDA (1979))
Compound class: Synthetic organic
Comment: The approved drug nadolol consists of equimolar amounts of four stereoisomers, therefore structures shown on other sites may vary in the representation of the stereochemistry. The structure shown here is representative of one of these isomers.
Click here for help
IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: nadolol

2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 6
Topological polar surface area 81.95
Molecular weight 309.19
XLogP 1.17
No. Lipinski's rules broken 0
Click here for help
Canonical SMILES OC(COc1cccc2c1CC(O)C(C2)O)CNC(C)(C)C
Isomeric SMILES OC(COc1cccc2c1C[C@H](O)[C@@H](C2)O)CNC(C)(C)C
InChI InChI=1S/C17H27NO4/c1-17(2,3)18-9-12(19)10-22-16-6-4-5-11-7-14(20)15(21)8-13(11)16/h4-6,12,14-15,18-21H,7-10H2,1-3H3/t12?,14-,15+/m1/s1
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1979))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
3875 nadolol
Synonyms Click here for help
Corgard® | corzide | SQ-11725
Database Links Click here for help
Specialist databases
GPCRdb Ligand nadolol
Reactome Drug Reactome logo R-ALL-9610982
Reactome Reaction Reactome logo R-HSA-9609310
Other databases
BindingDB Ligand 25766
CAS Registry No. 42200-33-9
DrugBank Ligand DB01203
GtoPdb PubChem SID 135650678
PubChem CID 39147
Search Google for chemical match using the InChIKey VWPOSFSPZNDTMJ-UCWKZMIHSA-N
Search Google for chemicals with the same backbone VWPOSFSPZNDTMJ
Search PubMed clinical trials nadolol
Search PubMed titles nadolol
Search PubMed titles/abstracts nadolol
UniChem Compound Search for chemical match using the InChIKey VWPOSFSPZNDTMJ-UCWKZMIHSA-N
UniChem Connectivity Search for chemical match using the InChIKey VWPOSFSPZNDTMJ-UCWKZMIHSA-N
Wikipedia Nadolol