revaprazan [Ligand Id: 12007] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1618279 (Revaprazan, SB-641257, YH-1885 FREE BASE) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| ATP4A in Pig [GtoPdb: 849] | ||||||||
| GtoPdb | - | - | 5.64 | pIC50 | 2300 | nM | IC50 | J Med Chem (2022) 65: 7843-7853 [PMID:35604136] |
| GtoPdb | Inhibitory activity against H+/K+ ATPase isolated from hog gastric mucosa | - | 6.46 | pIC50 | 350 | nM | IC50 | Bioorg Med Chem Lett (2010) 20: 5735-8 [PMID:20810280] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
