BayCysLT2 [Ligand Id: 6196] activity data from GtoPdb

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

  • CysLT1 receptor in Human [GtoPdb: 269] [UniProtKB: Q9Y271]
There should be some charts here, you may need to enable JavaScript!
  • CysLT2 receptor in Human [GtoPdb: 270] [UniProtKB: Q9NS75]
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
CysLT1 receptor in Human [GtoPdb: 269] [UniProtKB: Q9Y271]
GtoPdb - - 6.4 pA2 - - - FASEB J (2011) 25: 3519-28 [PMID:21753081]
CysLT2 receptor in Human [GtoPdb: 270] [UniProtKB: Q9NS75]
GtoPdb against 30-300nM LTD4 arrestin assay in C2C12 myofibroblasts - 7.28 pIC50 53 nM IC50 J Pharmacol Exp Ther (2011) 339: 768-78 [PMID:21903747]
GtoPdb against LTD4 Ca2+ mobilisation assay in COS-7 cells - 8.3 pA2 - - - FASEB J (2011) 25: 3519-28 [PMID:21753081]
GtoPdb against LTC4 and LTD4 Ca2+ mobilisation assays in HUVEC - 8.4 pA2 - - - FASEB J (2011) 25: 3519-28 [PMID:21753081]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.