verosudil   Click here for help

GtoPdb Ligand ID: 8911

Synonyms: AR 12286 | AR-12286
Compound class: Synthetic organic
Comment: Verosudil is an investigational Rho kinase inhibitor.
The INN record for verosudil indicates that this is a racemic mixture. We show the chemical structure without stereochemistry to represent the mixture. The (2S)-isomer is represented in PubChem CID 86270580 and the (2R)-isomer is represented in CID 44198631.
2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 93.44
Molecular weight 327.1
XLogP 1.83
No. Lipinski's rules broken 0
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Canonical SMILES CN(C(c1cscc1)C(=O)Nc1ccc2c(c1)cc[nH]c2=O)C
Isomeric SMILES CN(C(c1cscc1)C(=O)Nc1ccc2c(c1)cc[nH]c2=O)C
InChI InChI=1S/C17H17N3O2S/c1-20(2)15(12-6-8-23-10-12)17(22)19-13-3-4-14-11(9-13)5-7-18-16(14)21/h3-10,15H,1-2H3,(H,18,21)(H,19,22)
Classification Click here for help
Compound class Synthetic organic
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
10008 verosudil
Synonyms Click here for help
AR 12286 | AR-12286
Database Links Click here for help
CAS Registry No. 1414854-42-4
GtoPdb PubChem SID 310264692
PubChem CID 66906051
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UniChem Compound Search for chemical match using the InChIKey VDYRZXYYQMMFJW-UHFFFAOYSA-N
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