Synonyms: AR 12286 | AR-12286
Compound class:
Synthetic organic
Comment: Verosudil is an investigational Rho kinase inhibitor.
The INN record for verosudil indicates that this is a racemic mixture. We show the chemical structure without stereochemistry to represent the mixture. The (2S)-isomer is represented in PubChem CID 86270580 and the (2R)-isomer is represented in CID 44198631. |
|
Bioactivity Comments |
In humans topically applied verosudil is able to reduce intraocular pressure by more than 25% (administering 0.25% drug, twice daily) [1]. We have been unable to find publicly available, peer reviewed data quantifying the direct enzyme inhibitory action of this compound. |
Selectivity at enzymes | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
Key to terms and symbols | Click column headers to sort | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
|