mephenytoin   Click here for help

GtoPdb Ligand ID: 7223

Synonyms: Mesantoin®
Approved drug
mephenytoin is an approved drug (FDA (1946))
Compound class: Synthetic organic
Comment: Mephenytoin is a hydantoin class drug. It is no longer available in the US or the UK.
2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 52.9
Molecular weight 218.11
XLogP 1.85
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
Click here for help
Canonical SMILES CCC1(N=C(N(C1=O)C)O)c1ccccc1
Isomeric SMILES CCC1(N=C(N(C1=O)C)O)c1ccccc1
InChI InChI=1S/C12H14N2O2/c1-3-12(9-7-5-4-6-8-9)10(15)14(2)11(16)13-12/h4-8H,3H2,1-2H3,(H,13,16)
InChI Key GMHKMTDVRCWUDX-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1946))
IUPAC Name Click here for help
4-ethyl-2-hydroxy-1-methyl-4-phenyl-4,5-dihydro-1H-imidazol-5-one
International Nonproprietary Names Click here for help
INN number INN
1463 mephenytoin
Synonyms Click here for help
Mesantoin®
Database Links Click here for help
CAS Registry No. 50-12-4
ChEMBL Ligand CHEMBL861
DrugBank Ligand DB00532
DrugCentral Ligand 1695
GtoPdb PubChem SID 178103797
PubChem CID 4060
Search Google for chemical match using the InChIKey GMHKMTDVRCWUDX-UHFFFAOYSA-N
Search Google for chemicals with the same backbone GMHKMTDVRCWUDX
Search PubMed clinical trials mephenytoin
Search PubMed titles mephenytoin
Search PubMed titles/abstracts mephenytoin
Search UniChem for chemical match using the InChIKey GMHKMTDVRCWUDX-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone GMHKMTDVRCWUDX
Wikipedia Mephenytoin

Product suppliers

View disclaimer

Tocris
Mephenytoin
Cat. No. 3276