mephenytoin   Click here for help

GtoPdb Ligand ID: 7223

Synonyms: Mesantoin®
Approved drug
mephenytoin is an approved drug (FDA (1946))
Compound class: Synthetic organic
Comment: Mephenytoin is a hydantoin class drug. It is no longer available in the US or the UK.
2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 52.9
Molecular weight 218.11
XLogP 1.85
No. Lipinski's rules broken 0
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Canonical SMILES CCC1(N=C(N(C1=O)C)O)c1ccccc1
Isomeric SMILES CCC1(N=C(N(C1=O)C)O)c1ccccc1
InChI InChI=1S/C12H14N2O2/c1-3-12(9-7-5-4-6-8-9)10(15)14(2)11(16)13-12/h4-8H,3H2,1-2H3,(H,13,16)
Bioactivity Comments
Due to the complex and varied nature of the precise subunit composition of sodium channels receptors, and a paucity of affinity data with definitive molecular details, we have not tagged a primary target for this drug.