fampridine   Click here for help

GtoPdb Ligand ID: 2416

Synonyms: 4-aminopyridine | 4-AP | Ampyra® | EL-970
Approved drug
fampridine is an approved drug (FDA (2010), EMA (2011))
Compound class: Synthetic organic
Comment: Fampridine is the INN for this compound, whereas its USAN is dalfampridine.
Click here for help
2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Topological polar surface area 38.91
Molecular weight 94.05
XLogP -0.05
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
Click here for help
Canonical SMILES Nc1ccncc1
Isomeric SMILES Nc1ccncc1
InChI InChI=1S/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7)
InChI Key NUKYPUAOHBNCPY-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (2010), EMA (2011))
IUPAC Name Click here for help
pyridin-4-amine
International Nonproprietary Names Click here for help
INN number INN
7283 fampridine
Synonyms Click here for help
4-aminopyridine | 4-AP | Ampyra® | EL-970
Database Links Click here for help
BindingDB Ligand 10458
CAS Registry No. 504-24-5 (source: Scifinder)
ChEBI CHEBI:34385
ChEMBL Ligand CHEMBL284348
DrugBank Ligand DB06637
DrugCentral Ligand 4163
GtoPdb PubChem SID 135649796
PubChem CID 1727
Search Google for chemical match using the InChIKey NUKYPUAOHBNCPY-UHFFFAOYSA-N
Search Google for chemicals with the same backbone NUKYPUAOHBNCPY
Search PubMed clinical trials fampridine
Search PubMed titles fampridine
Search PubMed titles/abstracts fampridine
Search UniChem for chemical match using the InChIKey NUKYPUAOHBNCPY-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone NUKYPUAOHBNCPY
Wikipedia 4-Aminopyridine

Product suppliers

View disclaimer

Tocris
4-Aminopyridine
Cat. No. 0940