[3H]PSB-0413 [Ligand Id: 6147] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL369928 (PSB-0413)
  • P2Y12 receptor/Purinergic receptor P2Y12 in Human [ChEMBL: CHEMBL2001] [GtoPdb: 328] [UniProtKB: Q9H244]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
P2Y12 receptor/Purinergic receptor P2Y12 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2001] [GtoPdb: 328] [UniProtKB: Q9H244]
ChEMBL Binding affinity to P2Y12 receptor expressed in human platelets from 0.047 to 50 nM B 8.34 pKd 4.57 nM Kd Bioorg Med Chem Lett (2005) 15: 5450-5452 [PMID:16213725]
GtoPdb - - 8.5 pKd 3.16 nM Kd Purinergic Signal (2013) 9: 59-66 [PMID:22892887];
Bioorg Med Chem Lett (2005) 15: 5450-2 [PMID:16213725]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]