pramipexole

Ligand id: 953

Name: pramipexole

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View more information in the IUPHAR Pharmacology Education Project: pramipexole

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 79.18
Molecular weight 211.11
XLogP 0.4
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA and EMA (1997))
IUPAC Name
(6S)-N'-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
International Nonproprietary Names
INN number INN
6227 pramipexole
Synonyms
Mirapex® | Mirapexin® | Sifrol® | SND-919CL2Y | U-98528E
Comments
Marketed formulations may contain pramipexole dihydrochloride monohydrate (PubChem CID 166589).
Database Links
BindingDB Ligand 50226040
CAS Registry No. 104632-26-0
ChEBI CHEBI:8356
ChEMBL Ligand CHEMBL301265
DrugBank Ligand DB00413
GtoPdb PubChem SID 135650847
PubChem CID 119570
Search Google for chemical match using the InChIKey FASDKYOPVNHBLU-ZETCQYMHSA-N
Search Google for chemicals with the same backbone FASDKYOPVNHBLU
Search PubMed clinical trials pramipexole
Search PubMed titles pramipexole
Search PubMed titles/abstracts pramipexole
Search UniChem for chemical match using the InChIKey FASDKYOPVNHBLU-ZETCQYMHSA-N
Search UniChem for chemicals with the same backbone FASDKYOPVNHBLU
Wikipedia Pramipexole