amifampridine   

GtoPdb Ligand ID: 8032

Synonyms: 3,4-DAP | 3,4-diaminopyridine | Firdapse® | Ruzurgi® | Zenas®
amifampridine is an approved drug (EMA (2009), FDA (2018))
Compound class: Synthetic organic
Comment: Amifampridine is a potassium channel blocker.
2D Structure
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Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 0
Topological polar surface area 64.93
Molecular weight 109.06
XLogP -0.86
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
Canonical SMILES Nc1cnccc1N
Isomeric SMILES Nc1cnccc1N
InChI InChI=1S/C5H7N3/c6-4-1-2-8-3-5(4)7/h1-3H,7H2,(H2,6,8)
InChI Key OYTKINVCDFNREN-UHFFFAOYSA-N
Classification
Compound class Synthetic organic
Approved drug? Yes (EMA (2009), FDA (2018))
IUPAC Name
pyridine-3,4-diamine
International Nonproprietary Names
INN number INN
8804 amifampridine
Synonyms
3,4-DAP | 3,4-diaminopyridine | Firdapse® | Ruzurgi® | Zenas®
Database Links
CAS Registry No. 54-96-6
ChEMBL Ligand CHEMBL354077
DrugCentral Ligand 4336
GtoPdb PubChem SID 249565712
PubChem CID 5918
RCSB PDB Ligand L89
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Wikipedia 3,4-Diaminopyridine