amifampridine   Click here for help

GtoPdb Ligand ID: 8032

Synonyms: 3,4-DAP | 3,4-diaminopyridine | Firdapse® | Ruzurgi® | Zenas®
Approved drug PDB Ligand
amifampridine is an approved drug (EMA (2009), FDA (2018))
Compound class: Synthetic organic
Comment: Amifampridine is a potassium channel blocker.
2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 0
Topological polar surface area 64.93
Molecular weight 109.06
XLogP -0.86
No. Lipinski's rules broken 0
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Canonical SMILES Nc1cnccc1N
Isomeric SMILES Nc1cnccc1N
InChI InChI=1S/C5H7N3/c6-4-1-2-8-3-5(4)7/h1-3H,7H2,(H2,6,8)
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (EMA (2009), FDA (2018))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
8804 amifampridine
Synonyms Click here for help
3,4-DAP | 3,4-diaminopyridine | Firdapse® | Ruzurgi® | Zenas®
Database Links Click here for help
CAS Registry No. 54-96-6
ChEMBL Ligand CHEMBL354077
DrugCentral Ligand 4336
GtoPdb PubChem SID 249565712
PubChem CID 5918
RCSB PDB Ligand L89
Search Google for chemical match using the InChIKey OYTKINVCDFNREN-UHFFFAOYSA-N
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UniChem Compound Search for chemical match using the InChIKey OYTKINVCDFNREN-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey OYTKINVCDFNREN-UHFFFAOYSA-N
Wikipedia 3,4-Diaminopyridine