amatuximab   Click here for help

GtoPdb Ligand ID: 7750

Synonyms: MORAb-009
Compound class: Antibody
Comment: Amatuximab is a chimeric monoclonal antibody to mesothelin (MSLN; Q13421), a cell surface glycoprotein highly expressed in malignant pleural mesothelioma, all pancreatic adenocarcinoma, the majority of ovarian adenocarcinoma, as well as in non-small cell lung and colorectal cancers[5].
The crystal structure of the Fab fragment of amatuximab in complex with a mesothelin fragment (amino acids 7-64) has been deposited in Protein Data Bank with accession 4F33 [4].
Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
9343 amatuximab
Synonyms Click here for help
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 64
Other databases
GtoPdb PubChem SID 223366083
Search PubMed clinical trials amatuximab
Search PubMed titles amatuximab
Search PubMed titles/abstracts amatuximab
Wikipedia Amatuximab