phosphoenolpyruvic acid [Ligand Id: 4692] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1235228 (Oxo-Phosphonooxy-Acetic Acid) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| peptidase D/Xaa-Pro dipeptidase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4185] [GtoPdb: 2389] [UniProtKB: P12955] | ||||||||
| ChEMBL | Inhibitory constant for inhibition of prolidase in the second phase of biphasic inhibition | B | 3.62 | pKi | 0.24 | mM | Ki' | Bioorg Med Chem Lett (1995) 5: 627-630 |
| ChEMBL | Inhibitory constant for inhibition of prolidase in the first phase of biphasic inhibition | B | 6.52 | pKi | 300 | nM | Ki | Bioorg Med Chem Lett (1995) 5: 627-630 |
| ChEMBL | Inhibition of prolidase from swine kidney at a pH 6 | B | 8.07 | pKi | 8.5 | nM | Ki | Bioorg Med Chem Lett (1995) 5: 627-630 |
| peptidase D in Pig [GtoPdb: 2389] | ||||||||
| GtoPdb | Biphasic inhibition of purified enzyme from pig kidney. | - | 9.62 | pKi | 0.24 | nM | Ki | Bioorg Med Chem Lett (1995) 5: 627-630 |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
