ChEMBL ligand: CHEMBL315984
A1 receptor/Adenosine A1 receptor in Rat [ChEMBL: CHEMBL318] [GtoPdb: 18] [UniProtKB: P25099] There should be some charts here, you may need to enable JavaScript!
A2A receptor/Adenosine A2a receptor in Rat [ChEMBL: CHEMBL302] [GtoPdb: 19] [UniProtKB: P30543] There should be some charts here, you may need to enable JavaScript!
A3 receptor/Adenosine A3 receptor in Human [ChEMBL: CHEMBL256] [GtoPdb: 21] [UniProtKB: P0DMS8] A3 receptor/Adenosine A3 receptor in Rat [ChEMBL: CHEMBL3360] [GtoPdb: 21] [UniProtKB: P28647] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
A1 receptor/Adenosine A1 receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL318] [GtoPdb: 18] [UniProtKB: P25099]
ChEMBL	Displacement of specific [3H](R)-PIA binding at adenosine A1 receptor from rat brain membranes.	B	5.23	pKi	5930	nM	Ki	J Med Chem (1997) 40: 2596-2608 [PMID:9258367]
ChEMBL	Binding affinity against adenosine A1 receptor in rat cerebral cortex membrane by radioligand binding assay using [3H](R)-PIA.	B	5.23	pKi	5930	nM	Ki	J Med Chem (1996) 39: 4667-4675 [PMID:8917655]
ChEMBL	Displacement of [3H]-R-PIA from adenosine A1 receptor of rat brain membrane	B	5.23	pKi	5930	nM	Ki	J Med Chem (1999) 42: 3055-3065 [PMID:10447949]
ChEMBL	Displacement of [3H](R)-PIA binding to Adenosine A1 receptor in rat brain membranes	B	5.23	pKi	5930	nM	Ki	J Med Chem (1996) 39: 2980-2989 [PMID:8709132]
A2A receptor/Adenosine A2a receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL302] [GtoPdb: 19] [UniProtKB: P30543]
ChEMBL	Displacement of specific [3H]-CGS- 21680 binding at Adenosine A2A receptor in rat striatal membranes.	B	5.32	pKi	4770	nM	Ki	J Med Chem (1997) 40: 2596-2608 [PMID:9258367]
ChEMBL	Displacement of [3H]-CGS- 21680 from Adenosine A2A receptor of rat striatal membrane	B	5.32	pKi	4770	nM	Ki	J Med Chem (1996) 39: 4667-4675 [PMID:8917655]
ChEMBL	Displacement of [3H]CGS-21680 from Adenosine A2A receptor of rat striatal membrane at 10e-4 uM	B	5.32	pKi	4770	nM	Ki	J Med Chem (1999) 42: 3055-3065 [PMID:10447949]
ChEMBL	Displacement of [3H]-CGS- 21680 binding to Adenosine A2A receptor in rat striatal membranes	B	5.32	pKi	4770	nM	Ki	J Med Chem (1996) 39: 2980-2989 [PMID:8709132]
A3 receptor/Adenosine A3 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL256] [GtoPdb: 21] [UniProtKB: P0DMS8]
ChEMBL	Displacement of [125 I]AB-MECA from Adenosine A3 receptor expressed in HEK cells	B	6.96	pKi	110	nM	Ki	J Med Chem (1999) 42: 3055-3065 [PMID:10447949]
ChEMBL	Displacement of specific [125I]AB-MECA binding at human adenosine A3 receptor.	B	6.97	pKi	108	nM	Ki	J Med Chem (1997) 40: 2596-2608 [PMID:9258367]
ChEMBL	Inhibition of [125I]- AB-MECA binding to human Adenosine A3 receptors expressed in HEK cells	B	6.97	pKi	108	nM	Ki	J Med Chem (1996) 39: 4667-4675 [PMID:8917655]
ChEMBL	Displacement of [125]AB-MECA binding to human Adenosine A3 receptor expressed in HEK cells	B	6.97	pKi	108	nM	Ki	J Med Chem (1996) 39: 2980-2989 [PMID:8709132]
GtoPdb	-	-	7	pKi	-	-	-	Neuropharmacology (1997) 36: 1157-65 [PMID:9364471]; J Med Chem (1996) 39: 2980-9 [PMID:8709132]
A3 receptor/Adenosine A3 receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3360] [GtoPdb: 21] [UniProtKB: P28647]
ChEMBL	Binding affinity against rat Adenosine A3 receptor from CHO cells	B	5.38	pKi	4160	nM	Ki	J Med Chem (1996) 39: 2980-2989 [PMID:8709132]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]