corbadrine   Click here for help

GtoPdb Ligand ID: 508

Synonyms: α-Me-NE | α-methylnoradrenaline | α-methylnorepinephrine | levonordefrin | Neo-Cobefrin® | Nordefrin®
Approved drug
corbadrine is an approved drug (FDA (1960), in combination with mepivacaine hydrochloride)
Compound class: Synthetic organic
Comment: α-methylnoradrenaline (corbadrine) is a catecholamine sympathomimetic drug.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 2
Hydrogen bond donors 4
Rotatable bonds 2
Topological polar surface area 86.71
Molecular weight 183.09
XLogP 0.35
No. Lipinski's rules broken 0
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Canonical SMILES CC(C(c1ccc(c(c1)O)O)O)N
Isomeric SMILES C[C@@H]([C@@H](c1ccc(c(c1)O)O)O)N
InChI InChI=1S/C9H13NO3/c1-5(10)9(13)6-2-3-7(11)8(12)4-6/h2-5,9,11-13H,10H2,1H3/t5-,9-/m0/s1
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1960), in combination with mepivacaine hydrochloride)
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
50 corbadrine
Synonyms Click here for help
α-Me-NE | α-methylnoradrenaline | α-methylnorepinephrine | levonordefrin | Neo-Cobefrin® | Nordefrin®
Database Links Click here for help
Specialist databases
GPCRdb Ligand corbadrine
Other databases
BindingDB Ligand 50029048
CAS Registry No. 829-74-3 (source: Scifinder)
DrugBank Ligand DB06707
DrugCentral Ligand 4482
GtoPdb PubChem SID 135649925
PubChem CID 164739
Search Google for chemical match using the InChIKey GEFQWZLICWMTKF-CDUCUWFYSA-N
Search Google for chemicals with the same backbone GEFQWZLICWMTKF
Search PubMed clinical trials corbadrine
Search PubMed titles corbadrine
Search PubMed titles/abstracts corbadrine
UniChem Compound Search for chemical match using the InChIKey GEFQWZLICWMTKF-CDUCUWFYSA-N
UniChem Connectivity Search for chemical match using the InChIKey GEFQWZLICWMTKF-CDUCUWFYSA-N
Wikipedia Corbadrine